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| 07.05.2022 | 19:45 | FK Partizani | - | KF Tiranë | 1:2 (1:1) | |
| 08.05.2022 | 16:45 | KF Laçi | - | KS Kastrioti | 4:1 (2:1) | |
| 09.05.2022 | 16:45 | Dinamo Tiranë | - | KF Skënderbeu | 1:1 (0:0) | |
| 16:45 | KF Teuta Durrës | - | Egnatia Rrogozhine | 3:1 (2:0) | ||
| 19:45 | FK Vllaznia | - | FK Kukësi | 2:1 (1:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
KF Tiranë | 33 | 21 | 7 | 5 | 58:21 | 37 | 70 |
| 2 |
|
KF Laçi | 33 | 17 | 9 | 7 | 46:26 | 20 | 60 |
| 3 |
|
FK Partizani | 33 | 12 | 13 | 8 | 43:27 | 16 | 49 |
| 4 |
|
FK Vllaznia | 33 | 11 | 16 | 6 | 40:33 | 7 | 49 |
| 5 |
|
FK Kukësi | 33 | 12 | 10 | 11 | 44:41 | 3 | 46 |
| 6 |
|
KF Teuta Durrës | 33 | 11 | 10 | 12 | 36:43 | -7 | 43 |
| 7 |
|
KS Kastrioti | 33 | 13 | 4 | 16 | 29:46 | -17 | 43 |
| 8 |
|
Egnatia Rrogozhine | 33 | 8 | 10 | 15 | 28:44 | -16 | 34 |
| 9 |
|
KF Skënderbeu | 33 | 4 | 13 | 16 | 22:40 | -18 | 25 |
| 10 |
|
Dinamo Tiranë | 33 | 5 | 10 | 18 | 17:42 | -25 | 25 |
| Champions League Quali. | |
| Europa Conference League Quali. | |
| Relegation | |
| Abstieg |
