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| 29.10.2021 | 19:00 | ATSV Erlangen | - | ASV Cham | 5:1 (5:0) | |
| 30.10.2021 | 14:00 | Eintracht Bamberg | - | 1. FC Sand | 6:0 (3:0) | |
| 14:00 | ASV Neumarkt | - | SpVgg Bayern Hof | 2:0 (1:0) | ||
| 14:00 | TSV Karlburg | - | SV Seligenporten | 0:0 (0:0) | ||
| 14:00 | DJK Gebenbach | - | SpVgg Ansbach | 2:3 (0:1) | ||
| 14:00 | Würzburger FV | - | DJK Ammerthal | 0:3 (0:3) | ||
| 15:00 | Vatan Spor Aschaffenburg | - | TSV Abtswind | 1:2 (0:1) | ||
| 15:00 | DJK Vilzing | - | TSV Großbardorf | 1:2 (1:1) | ||
| 31.10.2021 | 15:00 | DJK Bamberg | - | 1. SC Feucht | 1:0 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SpVgg Ansbach | 18 | 14 | 2 | 2 | 42:15 | 27 | 44 |
| 2 |
|
Eintracht Bamberg | 18 | 13 | 3 | 2 | 51:12 | 39 | 42 |
| 3 |
|
DJK Vilzing | 18 | 13 | 1 | 4 | 39:17 | 22 | 40 |
| 4 |
|
ATSV Erlangen | 18 | 12 | 2 | 4 | 39:19 | 20 | 38 |
| 5 |
|
DJK Ammerthal | 18 | 11 | 2 | 5 | 44:27 | 17 | 35 |
| 6 |
|
ASV Neumarkt | 18 | 11 | 2 | 5 | 38:23 | 15 | 35 |
| 7 |
|
1. SC Feucht | 18 | 8 | 4 | 6 | 27:21 | 6 | 28 |
| 8 |
|
TSV Abtswind | 18 | 8 | 2 | 8 | 26:25 | 1 | 26 |
| 9 |
|
DJK Bamberg | 18 | 8 | 2 | 8 | 28:30 | -2 | 26 |
| 10 |
|
DJK Gebenbach | 18 | 7 | 2 | 9 | 40:39 | 1 | 23 |
| 11 |
|
TSV Großbardorf | 18 | 7 | 2 | 9 | 25:36 | -11 | 23 |
| 12 |
|
SpVgg Bayern Hof | 18 | 5 | 4 | 9 | 33:42 | -9 | 19 |
| 13 |
|
TSV Karlburg | 18 | 3 | 10 | 5 | 14:23 | -9 | 19 |
| 14 |
|
Würzburger FV | 18 | 4 | 2 | 12 | 16:39 | -23 | 14 |
| 15 |
|
1. FC Sand | 18 | 3 | 5 | 10 | 14:37 | -23 | 14 |
| 16 |
|
SV Seligenporten | 18 | 3 | 3 | 12 | 22:44 | -22 | 12 |
| 17 |
|
Vatan Spor Aschaffenburg | 18 | 2 | 5 | 11 | 17:38 | -21 | 11 |
| 18 |
|
ASV Cham | 18 | 2 | 3 | 13 | 21:49 | -28 | 9 |
| Aufstieg | |
| Playoffs | |
| Relegation | |
| Abstieg |
