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| 05.11.2021 | 18:30 | SV Seligenporten | - | ASV Neumarkt | 2:3 (0:2) | |
| 06.11.2021 | 14:00 | 1. FC Sand | - | DJK Bamberg | 1:2 (0:0) | |
| 14:00 | SpVgg Ansbach | - | ATSV Erlangen | 0:4 (0:1) | ||
| 14:00 | TSV Abtswind | - | DJK Vilzing | 2:3 (0:2) | ||
| 14:00 | TSV Großbardorf | - | TSV Karlburg | 1:0 (0:0) | ||
| 14:00 | Würzburger FV | - | Vatan Spor Aschaffenburg | 4:2 (4:0) | ||
| 15:00 | ASV Cham | - | DJK Ammerthal | 0:1 (0:1) | ||
| 16.11.2021 | 19:00 | 1. SC Feucht | - | DJK Gebenbach | 2:2 (2:1) | |
| 06.04.2022 | 18:00 | SpVgg Bayern Hof | - | Eintracht Bamberg | 0:1 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Eintracht Bamberg | 19 | 14 | 3 | 2 | 52:12 | 40 | 45 |
| 2 |
|
SpVgg Ansbach | 19 | 14 | 2 | 3 | 42:19 | 23 | 44 |
| 3 |
|
DJK Vilzing | 19 | 14 | 1 | 4 | 42:19 | 23 | 43 |
| 4 |
|
ATSV Erlangen | 19 | 13 | 2 | 4 | 43:19 | 24 | 41 |
| 5 |
|
DJK Ammerthal | 19 | 12 | 2 | 5 | 45:27 | 18 | 38 |
| 6 |
|
ASV Neumarkt | 19 | 12 | 2 | 5 | 41:25 | 16 | 38 |
| 7 |
|
1. SC Feucht | 19 | 8 | 5 | 6 | 29:23 | 6 | 29 |
| 8 |
|
DJK Bamberg | 19 | 9 | 2 | 8 | 30:31 | -1 | 29 |
| 9 |
|
TSV Abtswind | 19 | 8 | 2 | 9 | 28:28 | 0 | 26 |
| 10 |
|
TSV Großbardorf | 19 | 8 | 2 | 9 | 26:36 | -10 | 26 |
| 11 |
|
DJK Gebenbach | 19 | 7 | 3 | 9 | 42:41 | 1 | 24 |
| 12 |
|
SpVgg Bayern Hof | 19 | 5 | 4 | 10 | 33:43 | -10 | 19 |
| 13 |
|
TSV Karlburg | 19 | 3 | 10 | 6 | 14:24 | -10 | 19 |
| 14 |
|
Würzburger FV | 19 | 5 | 2 | 12 | 20:41 | -21 | 17 |
| 15 |
|
1. FC Sand | 19 | 3 | 5 | 11 | 15:39 | -24 | 14 |
| 16 |
|
SV Seligenporten | 19 | 3 | 3 | 13 | 24:47 | -23 | 12 |
| 17 |
|
Vatan Spor Aschaffenburg | 19 | 2 | 5 | 12 | 19:42 | -23 | 11 |
| 18 |
|
ASV Cham | 19 | 2 | 3 | 14 | 21:50 | -29 | 9 |
| Aufstieg | |
| Playoffs | |
| Relegation | |
| Abstieg |
