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| 22.04.2022 | 18:30 | SV Seligenporten | - | DJK Gebenbach | 3:4 (1:2) | |
| 23.04.2022 | 14:00 | Eintracht Bamberg | - | DJK Vilzing | 0:1 (0:0) | |
| 14:00 | ASV Neumarkt | - | TSV Karlburg | 3:0 (0:0) | ||
| 15:00 | SpVgg Bayern Hof | - | ATSV Erlangen | 0:4 (0:1) | ||
| 15:00 | Würzburger FV | - | 1. SC Feucht | 1:3 (0:0) | ||
| 16:00 | 1. FC Sand | - | DJK Ammerthal | 0:3 (0:0) | ||
| 16:00 | TSV Abtswind | - | ASV Cham | 2:0 (1:0) | ||
| 16:30 | TSV Großbardorf | - | SpVgg Ansbach | 0:3 (0:1) | ||
| 24.04.2022 | 15:00 | DJK Bamberg | - | Vatan Spor Aschaffenburg | 5:1 (2:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
DJK Vilzing | 30 | 22 | 3 | 5 | 71:26 | 45 | 69 |
| 2 |
|
SpVgg Ansbach | 30 | 22 | 3 | 5 | 70:29 | 41 | 69 |
| 3 |
|
ATSV Erlangen | 30 | 21 | 3 | 6 | 72:31 | 41 | 66 |
| 4 |
|
Eintracht Bamberg | 30 | 20 | 5 | 5 | 75:26 | 49 | 65 |
| 5 |
|
ASV Neumarkt | 30 | 17 | 4 | 9 | 62:40 | 22 | 55 |
| 6 |
|
DJK Bamberg | 30 | 15 | 4 | 11 | 61:52 | 9 | 49 |
| 7 |
|
DJK Ammerthal | 30 | 15 | 4 | 11 | 61:60 | 1 | 49 |
| 8 |
|
TSV Abtswind | 30 | 15 | 2 | 13 | 44:44 | 0 | 47 |
| 9 |
|
DJK Gebenbach | 30 | 14 | 4 | 12 | 66:57 | 9 | 46 |
| 10 |
|
1. SC Feucht | 30 | 13 | 5 | 12 | 49:38 | 11 | 44 |
| 11 |
|
TSV Großbardorf | 30 | 12 | 4 | 14 | 49:52 | -3 | 40 |
| 12 |
|
SpVgg Bayern Hof | 30 | 10 | 5 | 15 | 51:62 | -11 | 35 |
| 13 |
|
ASV Cham | 30 | 8 | 4 | 18 | 43:67 | -24 | 28 |
| 14 |
|
Würzburger FV | 30 | 7 | 7 | 16 | 35:59 | -24 | 28 |
| 15 |
|
TSV Karlburg | 30 | 4 | 11 | 15 | 19:50 | -31 | 23 |
| 16 |
|
Vatan Spor Aschaffenburg | 30 | 5 | 6 | 19 | 29:68 | -39 | 21 |
| 17 |
|
SV Seligenporten | 30 | 5 | 3 | 22 | 37:88 | -51 | 18 |
| 18 |
|
1. FC Sand | 30 | 4 | 5 | 21 | 22:67 | -45 | 17 |
| Aufstieg | |
| Playoffs | |
| Relegation | |
| Abstieg |
