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| 29.04.2022 | 19:00 | 1. SC Feucht | - | ASV Neumarkt | 0:2 (0:1) | |
| 19:00 | ATSV Erlangen | - | SV Seligenporten | 2:1 (0:0) | ||
| 30.04.2022 | 14:00 | SpVgg Ansbach | - | TSV Abtswind | 6:0 (3:0) | |
| 15:00 | DJK Vilzing | - | DJK Bamberg | 4:0 (4:0) | ||
| 15:00 | Vatan Spor Aschaffenburg | - | 1. FC Sand | 3:1 (2:0) | ||
| 15:00 | DJK Ammerthal | - | SpVgg Bayern Hof | 2:4 (1:0) | ||
| 16:00 | ASV Cham | - | Würzburger FV | 1:0 (0:0) | ||
| 16:00 | DJK Gebenbach | - | TSV Großbardorf | 1:1 (1:0) | ||
| 16:00 | TSV Karlburg | - | Eintracht Bamberg | 0:3 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
DJK Vilzing | 31 | 23 | 3 | 5 | 75:26 | 49 | 72 |
| 2 |
|
SpVgg Ansbach | 31 | 23 | 3 | 5 | 76:29 | 47 | 72 |
| 3 |
|
ATSV Erlangen | 31 | 22 | 3 | 6 | 74:32 | 42 | 69 |
| 4 |
|
Eintracht Bamberg | 31 | 21 | 5 | 5 | 78:26 | 52 | 68 |
| 5 |
|
ASV Neumarkt | 31 | 18 | 4 | 9 | 64:40 | 24 | 58 |
| 6 |
|
DJK Bamberg | 31 | 15 | 4 | 12 | 61:56 | 5 | 49 |
| 7 |
|
DJK Ammerthal | 31 | 15 | 4 | 12 | 63:64 | -1 | 49 |
| 8 |
|
DJK Gebenbach | 31 | 14 | 5 | 12 | 67:58 | 9 | 47 |
| 9 |
|
TSV Abtswind | 31 | 15 | 2 | 14 | 44:50 | -6 | 47 |
| 10 |
|
1. SC Feucht | 31 | 13 | 5 | 13 | 49:40 | 9 | 44 |
| 11 |
|
TSV Großbardorf | 31 | 12 | 5 | 14 | 50:53 | -3 | 41 |
| 12 |
|
SpVgg Bayern Hof | 31 | 11 | 5 | 15 | 55:64 | -9 | 38 |
| 13 |
|
ASV Cham | 31 | 9 | 4 | 18 | 44:67 | -23 | 31 |
| 14 |
|
Würzburger FV | 31 | 7 | 7 | 17 | 35:60 | -25 | 28 |
| 15 |
|
Vatan Spor Aschaffenburg | 31 | 6 | 6 | 19 | 32:69 | -37 | 24 |
| 16 |
|
TSV Karlburg | 31 | 4 | 11 | 16 | 19:53 | -34 | 23 |
| 17 |
|
SV Seligenporten | 31 | 5 | 3 | 23 | 38:90 | -52 | 18 |
| 18 |
|
1. FC Sand | 31 | 4 | 5 | 22 | 23:70 | -47 | 17 |
| Aufstieg | |
| Playoffs | |
| Relegation | |
| Abstieg |
