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| H | Internacional | - | Flamengo RJ | 1:1 (1:0) | ||
| R | Flamengo RJ | - | Internacional | 1:0 (1:0) | ||
| H: 13.08.2022 16:00 | R: 17.08.2022 20:15 | Sieger: Flamengo RJ | ||||
| H | São Paulo FC | - | Athletico Paranaense | 3:1 (1:0) | ||
| R | Athletico Paranaense | - | São Paulo FC | 4:1 (1:1) | ||
| H: 13.08.2022 19:00 | R: 19.08.2022 20:30 | Sieger: Athletico Paranaense | ||||
| H | Vasco da Gama | - | Palmeiras | 1:0 (0:0) | ||
| R | Palmeiras | - | Vasco da Gama | 4:3 (1:0, 1:0, 1:0) i.E. | ||
| H: 14.08.2022 21:00 | R: 18.08.2022 20:00 | Sieger: Palmeiras | ||||
| H | América - MG | - | Corinthians SP | 0:2 (0:1) | ||
| R | Corinthians SP | - | América - MG | 4:2 (0:1, 0:2, 0:2) i.E. | ||
| H: 15.08.2022 21:30 | R: 21.08.2022 21:00 | Sieger: Corinthians SP | ||||
