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| 21.02.1981 | 15:30 | 1. FC Köln | - | TSV 1860 München | 4:1 (4:1) | |
| 15:30 | Eintracht Frankfurt | - | Hamburger SV | 1:1 (0:0) | ||
| 15:30 | Bayer 05 Uerdingen | - | SV Bayer 04 Leverkusen | 3:0 (2:0) | ||
| 15:30 | Bayern München | - | Arminia Bielefeld | 5:1 (4:0) | ||
| 15:30 | Borussia Dortmund | - | FC Schalke 04 | 2:2 (1:0) | ||
| 15:30 | 1. FC Nürnberg | - | MSV Duisburg | 1:0 (0:0) | ||
| 15:30 | Fortuna Düsseldorf | - | Karlsruher SC | 1:2 (0:2) | ||
| 24.03.1981 | 20:00 | 1. FC Kaiserslautern | - | VfL Bochum | 0:0 (0:0) | |
| 24.04.1981 | 20:00 | Bor. Mönchengladbach | - | VfB Stuttgart | 1:3 (0:1) |
| » Tabelle | Heim | Auswärts | Hinrunde | Rückrunde | 1. Halbzeit | 2. Halbzeit |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Hamburger SV | 22 | 15 | 4 | 3 | 51:24 | 27 | 34:10 |
| 2 |
|
Bayern München | 22 | 14 | 6 | 2 | 55:29 | 26 | 34:10 |
| 3 |
|
1. FC Kaiserslautern | 22 | 11 | 6 | 5 | 41:25 | 16 | 28:16 |
| 4 |
|
VfB Stuttgart | 22 | 11 | 6 | 5 | 44:30 | 14 | 28:16 |
| 5 |
|
Eintracht Frankfurt | 22 | 10 | 6 | 6 | 41:35 | 6 | 26:18 |
| 6 |
|
1. FC Köln | 22 | 9 | 6 | 7 | 40:34 | 6 | 24:20 |
| 7 |
|
Borussia Dortmund | 22 | 8 | 7 | 7 | 46:39 | 7 | 23:21 |
| 8 |
|
VfL Bochum | 22 | 6 | 11 | 5 | 35:28 | 7 | 23:21 |
| 9 |
|
Karlsruher SC | 22 | 6 | 10 | 6 | 32:39 | -7 | 22:22 |
| 10 |
|
Bor. Mönchengladbach | 22 | 8 | 5 | 9 | 38:44 | -6 | 21:23 |
| 11 |
|
MSV Duisburg | 22 | 6 | 7 | 9 | 28:35 | -7 | 19:25 |
| 12 |
|
1. FC Nürnberg | 22 | 7 | 4 | 11 | 33:38 | -5 | 18:26 |
| 13 |
|
SV Bayer 04 Leverkusen | 22 | 4 | 9 | 9 | 29:37 | -8 | 17:27 |
| 14 |
|
Fortuna Düsseldorf | 22 | 5 | 7 | 10 | 38:47 | -9 | 17:27 |
| 15 |
|
Bayer 05 Uerdingen | 22 | 6 | 5 | 11 | 34:43 | -9 | 17:27 |
| 16 |
|
TSV 1860 München | 22 | 6 | 5 | 11 | 32:45 | -13 | 17:27 |
| 17 |
|
FC Schalke 04 | 22 | 5 | 6 | 11 | 33:59 | -26 | 16:28 |
| 18 |
|
Arminia Bielefeld | 22 | 3 | 6 | 13 | 30:49 | -19 | 12:32 |
