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| H | Bayern München | - | Omonia Nikosia | 9:0 (4:0) | ||
| R | Omonia Nikosia | - | Bayern München | 0:4 (0:2) | ||
| H: 24.10.1972 20:00 | R: 26.10.1972 20:00 | Sieger: Bayern München | ||||
| H | Argeș Pitești | - | Real Madrid | 2:1 (1:1) | ||
| R | Real Madrid | - | Argeș Pitești | 3:1 (1:1) | ||
| H: 25.10.1972 14:00 | R: 09.11.1972 20:30 | Sieger: Real Madrid | ||||
| H | TJ Spartak TAZ Trnava | - | RSC Anderlecht | 1:0 (0:0) | ||
| R | RSC Anderlecht | - | TJ Spartak TAZ Trnava | 0:1 (0:0) | ||
| H: 25.10.1972 14:30 | R: 08.11.1972 20:00 | Sieger: TJ Spartak TAZ Trnava | ||||
| H | Dinamo Kiev | - | Górnik Zabrze | 2:0 (0:0) | ||
| R | Górnik Zabrze | - | Dinamo Kiev | 2:1 (1:1) | ||
| H: 25.10.1972 18:00 | R: 08.11.1972 13:30 | Sieger: Dinamo Kiev | ||||
| H | Derby County | - | SL Benfica | 3:0 (3:0) | ||
| R | SL Benfica | - | Derby County | 0:0 (0:0) | ||
| H: 25.10.1972 20:30 | R: 08.11.1972 22:45 | Sieger: Derby County | ||||
| H | Juventus | - | 1. FC Magdeburg | 1:0 (0:0) | ||
| R | 1. FC Magdeburg | - | Juventus | 0:1 (0:0) | ||
| H: 25.10.1972 21:00 | R: 08.11.1972 18:00 | Sieger: Juventus | ||||
| H | Celtic FC | - | Újpesti Dózsa SC | 2:1 (0:1) | ||
| R | Újpesti Dózsa SC | - | Celtic FC | 3:0 (3:0) | ||
| H: 25.10.1972 21:00 | R: 08.11.1972 17:00 | Sieger: Újpesti Dózsa SC | ||||
| H | CSKA Sofia | - | AFC Ajax | 1:3 (1:2) | ||
| R | AFC Ajax | - | CSKA Sofia | 3:0 (2:0) | ||
| H: 08.11.1972 17:00 | R: 29.11.1972 20:15 | Sieger: AFC Ajax | ||||
