 |
 |
|
|
| 12.09.2021 | 20:00 | Santiago Wanderers | - | Cobresal | 2:1 (1:1) | |
| 22:30 | Audax Italiano | - | Unión La Calera | 2:3 (2:1) | ||
| 13.09.2021 | 01:00 | Curicó Unido | - | Universidad Católica | 2:4 (2:2) | |
| 21:30 | Ñublense | - | Huachipato | 2:2 (0:2) | ||
| 14.09.2021 | 00:00 | Unión Española | - | Universidad de Chile | 2:3 (1:2) | |
| 19:00 | La Serena | - | O'Higgins | 2:0 (1:0) | ||
| 15.09.2021 | 00:00 | Colo-Colo | - | Everton | 2:0 (0:0) | |
| 21:00 | Palestino | - | Melipilla | 3:1 (3:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Colo-Colo | 20 | 12 | 4 | 4 | 32:17 | 15 | 40 |
| 2 |
|
Universidad Católica | 20 | 11 | 2 | 7 | 35:27 | 8 | 35 |
| 3 |
|
Unión La Calera | 20 | 10 | 5 | 5 | 23:22 | 1 | 35 |
| 4 |
|
Audax Italiano | 20 | 9 | 7 | 4 | 24:19 | 5 | 34 |
| 5 |
|
Universidad de Chile | 19 | 9 | 6 | 4 | 26:18 | 8 | 33 |
| 6 |
|
Unión Española | 20 | 9 | 3 | 8 | 32:28 | 4 | 30 |
| 7 |
|
Cobresal | 20 | 8 | 5 | 7 | 26:21 | 5 | 29 |
| 8 |
|
Antofagasta | 19 | 7 | 7 | 5 | 24:22 | 2 | 28 |
| 9 |
|
Everton | 20 | 7 | 6 | 7 | 17:19 | -2 | 27 |
| 10 |
|
Ñublense | 20 | 6 | 8 | 6 | 30:26 | 4 | 26 |
| 11 |
|
La Serena | 20 | 6 | 7 | 7 | 27:24 | 3 | 25 |
| 12 |
|
Palestino | 20 | 7 | 3 | 10 | 28:30 | -2 | 24 |
| 13 |
|
Huachipato | 19 | 4 | 10 | 5 | 24:25 | -1 | 22 |
| 14 |
|
O'Higgins | 20 | 5 | 7 | 8 | 16:26 | -10 | 22 |
| 15 |
|
Melipilla | 20 | 5 | 5 | 10 | 24:35 | -11 | 20 |
| 16 |
|
Curicó Unido | 20 | 4 | 7 | 9 | 23:30 | -7 | 19 |
| 17 |
|
Santiago Wanderers | 19 | 2 | 2 | 15 | 12:34 | -22 | 8 |
| Copa Libertadores | |
| Qualifikation | |
| Copa Sudamericana | |
| Relegation | |
| Abstieg |
