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| 21.03.2022 | 21:45 | Jaguares de Córdoba | - | Unión Magdalena | 2:0 (1:0) | |
| 22.03.2022 | 00:10 | Deportivo Cali | - | Atlético Nacional | 3:3 (3:0) | |
| 02:15 | Santa Fe | - | Atlético Bucaramanga | 3:1 (1:0) | ||
| 23.03.2022 | 00:00 | Once Caldas | - | Deportes Tolima | 2:2 (0:2) | |
| 02:05 | Patriotas FC | - | América de Cali | 2:1 (1:1) | ||
| 20:00 | Cortuluá | - | Envigado FC | 1:1 (0:1) | ||
| 22:05 | La Equidad | - | Alianza Petrolera | 2:1 (1:0) | ||
| 24.03.2022 | 00:10 | Águilas Doradas | - | Deportivo Pereira | 1:0 (0:0) | |
| 02:15 | Independiente Medellín | - | Millonarios | 1:0 (1:0) | ||
| 25.03.2022 | 22:00 | Atlético Junior | - | Deportivo Pasto | 1:1 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Millonarios | 12 | 8 | 2 | 2 | 13:4 | 9 | 26 |
| 2 |
|
Atlético Nacional | 12 | 7 | 3 | 2 | 19:11 | 8 | 24 |
| 3 |
|
Deportes Tolima | 12 | 7 | 2 | 3 | 17:10 | 7 | 23 |
| 4 |
|
Independiente Medellín | 12 | 7 | 0 | 5 | 17:11 | 6 | 21 |
| 5 |
|
Once Caldas | 12 | 5 | 5 | 2 | 13:9 | 4 | 20 |
| 6 |
|
Envigado FC | 12 | 5 | 4 | 3 | 15:12 | 3 | 19 |
| 7 |
|
Santa Fe | 12 | 5 | 4 | 3 | 19:17 | 2 | 19 |
| 8 |
|
Atlético Junior | 12 | 6 | 1 | 5 | 15:13 | 2 | 19 |
| 9 |
|
La Equidad | 12 | 4 | 5 | 3 | 13:11 | 2 | 17 |
| 10 |
|
Alianza Petrolera | 12 | 3 | 7 | 2 | 14:12 | 2 | 16 |
| 11 |
|
Cortuluá | 12 | 4 | 4 | 4 | 13:13 | 0 | 16 |
| 12 |
|
Jaguares de Córdoba | 12 | 5 | 1 | 6 | 15:18 | -3 | 16 |
| 13 |
|
Atlético Bucaramanga | 12 | 4 | 3 | 5 | 15:16 | -1 | 15 |
| 14 |
|
América de Cali | 12 | 4 | 3 | 5 | 13:14 | -1 | 15 |
| 15 |
|
Deportivo Pereira | 12 | 4 | 2 | 6 | 13:15 | -2 | 14 |
| 16 |
|
Águilas Doradas | 12 | 4 | 2 | 6 | 10:17 | -7 | 14 |
| 17 |
|
Patriotas FC | 12 | 3 | 3 | 6 | 12:16 | -4 | 12 |
| 18 |
|
Deportivo Pasto | 12 | 2 | 4 | 6 | 8:14 | -6 | 10 |
| 19 |
|
Deportivo Cali | 12 | 2 | 2 | 8 | 8:16 | -8 | 8 |
| 20 |
|
Unión Magdalena | 12 | 1 | 3 | 8 | 5:18 | -13 | 6 |
| Nächste Runde |
