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| H | Deportivo Saprissa | - | LD Alajuelense | 4:3 (3:1) | ||
| R | LD Alajuelense | - | Deportivo Saprissa | 2:2 (0:1) | ||
| H: 17.05.2021 05:30 | R: 20.05.2021 05:00 | Sieger: Deportivo Saprissa | ||||
| H | CS Herediano | - | Santos de Guápiles | 2:1 (1:0) | ||
| R | Santos de Guápiles | - | CS Herediano | 0:0 (0:0) | ||
| H: 18.05.2021 05:00 | R: 21.05.2021 05:00 | Sieger: CS Herediano | ||||
