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| 19.08.2021 | 21:00 | Pyramids FC | - | Aswan SC | 2:0 (1:0) | |
| 20.08.2021 | 19:00 | Ismaily | - | Wadi Degla SC | 0:2 (0:0) | |
| 21:00 | ENPPI | - | Tala'ea El Gaish SC | 1:1 (1:1) | ||
| 21:00 | Al Ahly SC | - | Al Masry Club | 4:2 (3:2) | ||
| 21:00 | Ceramica Cleopatra | - | Zamalek | 1:2 (1:1) | ||
| 21.08.2021 | 19:00 | National Bank SC | - | Ghazl Al Mehalla | 1:1 (1:0) | |
| 19:00 | El Entag El Harby | - | Ittihad El Iskandary | 1:1 (1:0) | ||
| 21:00 | Smouha Sporting Club | - | El Gouna | 3:1 (2:1) | ||
| 21:00 | Al Mokawloon | - | Misr lel-Maqasah SC | 3:2 (1:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Zamalek | 32 | 23 | 7 | 2 | 58:20 | 38 | 76 |
| 2 |
|
Al Ahly SC | 32 | 21 | 9 | 2 | 67:25 | 42 | 72 |
| 3 |
|
Smouha Sporting Club | 32 | 11 | 17 | 4 | 51:40 | 11 | 50 |
| 4 |
|
Pyramids FC | 32 | 11 | 16 | 5 | 46:37 | 9 | 49 |
| 5 |
|
Al Masry Club | 32 | 13 | 10 | 9 | 43:35 | 8 | 49 |
| 6 |
|
Ittihad El Iskandary | 32 | 11 | 11 | 10 | 35:35 | 0 | 44 |
| 7 |
|
ENPPI | 32 | 10 | 13 | 9 | 34:34 | 0 | 43 |
| 8 |
|
Tala'ea El Gaish SC | 32 | 10 | 10 | 12 | 41:37 | 4 | 40 |
| 9 |
|
Ceramica Cleopatra | 32 | 8 | 14 | 10 | 39:43 | -4 | 38 |
| 10 |
|
Al Mokawloon | 32 | 10 | 8 | 14 | 35:44 | -9 | 38 |
| 11 |
|
Misr lel-Maqasah SC | 32 | 10 | 7 | 15 | 36:49 | -13 | 37 |
| 12 |
|
El Gouna | 32 | 8 | 13 | 11 | 33:38 | -5 | 37 |
| 13 |
|
Ghazl Al Mehalla | 32 | 7 | 14 | 11 | 27:39 | -12 | 35 |
| 14 |
|
Ismaily | 32 | 9 | 10 | 13 | 39:42 | -3 | 34 |
| 15 |
|
National Bank SC | 32 | 6 | 15 | 11 | 38:43 | -5 | 33 |
| 16 |
|
Wadi Degla SC | 32 | 5 | 13 | 14 | 29:38 | -9 | 28 |
| 17 |
|
El Entag El Harby | 32 | 5 | 12 | 15 | 35:58 | -23 | 27 |
| 18 |
|
Aswan SC | 32 | 6 | 9 | 17 | 27:56 | -29 | 27 |
| Champions League | |
| Confederation Cup | |
| Abstieg |
|
# Ismaily wurden 3 Punkte abgezogen. |
