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| 20.01.2019 | 11:30 | Sevilla Atlético | - | CD El Ejido 2012 | 1:0 (0:0) | |
| 11:30 | UD Almería B | - | CF Talavera | 2:2 (1:2) | ||
| 12:00 | Atlético Sanluqueño CF | - | UD Ibiza | 0:1 (0:0) | ||
| 12:00 | UD Melilla | - | San Fernando CD | 3:1 (1:1) | ||
| 12:00 | Atlético Malagueño | - | Marbella FC | 0:1 (0:1) | ||
| 12:00 | FC Jumilla | - | RB Linense | 2:1 (2:1) | ||
| 12:00 | UCAM Murcia CF | - | Recreativo Granada | 3:0 (3:0) | ||
| 17:00 | Recreativo Huelva | - | CD Badajoz | 2:1 (1:0) | ||
| 17:00 | CF Villanovense | - | Real Murcia | 0:0 (0:0) | ||
| 17:00 | FC Cartagena | - | Don Benito | 4:0 (2:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Cartagena | 21 | 14 | 3 | 4 | 38:12 | 26 | 45 |
| 2 |
|
UCAM Murcia CF | 21 | 14 | 2 | 5 | 33:15 | 18 | 44 |
| 3 |
|
UD Melilla | 21 | 12 | 5 | 4 | 30:17 | 13 | 41 |
| 4 |
|
Recreativo Huelva | 21 | 11 | 4 | 6 | 25:18 | 7 | 37 |
| 5 |
|
San Fernando CD | 21 | 10 | 6 | 5 | 22:15 | 7 | 36 |
| 6 |
|
UD Ibiza | 21 | 10 | 4 | 7 | 22:18 | 4 | 34 |
| 7 |
|
Real Murcia | 21 | 8 | 10 | 3 | 20:12 | 8 | 34 |
| 8 |
|
RB Linense | 21 | 8 | 9 | 4 | 22:13 | 9 | 33 |
| 9 |
|
FC Jumilla | 21 | 7 | 8 | 6 | 21:20 | 1 | 29 |
| 10 |
|
CD Badajoz | 21 | 8 | 5 | 8 | 22:24 | -2 | 29 |
| 11 |
|
CF Talavera | 21 | 7 | 6 | 8 | 21:18 | 3 | 27 |
| 12 |
|
Marbella FC | 21 | 8 | 2 | 11 | 19:27 | -8 | 26 |
| 13 |
|
Recreativo Granada | 21 | 7 | 4 | 10 | 22:26 | -4 | 25 |
| 14 |
|
CD El Ejido 2012 | 21 | 7 | 4 | 10 | 18:26 | -8 | 25 |
| 15 |
|
Sevilla Atlético | 21 | 6 | 5 | 10 | 20:27 | -7 | 23 |
| 16 |
|
CF Villanovense | 21 | 4 | 10 | 7 | 18:22 | -4 | 22 |
| 17 |
|
Atlético Sanluqueño CF | 21 | 5 | 6 | 10 | 17:31 | -14 | 21 |
| 18 |
|
Don Benito | 21 | 4 | 5 | 12 | 15:29 | -14 | 17 |
| 19 |
|
UD Almería B | 21 | 4 | 4 | 13 | 19:37 | -18 | 16 |
| 20 |
|
Atlético Malagueño | 21 | 3 | 4 | 14 | 13:30 | -17 | 13 |
| Playoffs | |
| Playoffs | |
| Relegation | |
| Abstieg |
