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| 18.02.2006 | 18:30 | Lorca Deportiva | - | Albacete | 3:0 (0:0) | |
| 18:30 | Sporting Gijón | - | Atlético Malagueño | 0:0 (0:0) | ||
| 18:30 | Ciudad de Murcia | - | UD Almería | 0:0 (0:0) | ||
| 19:00 | Hércules CF | - | CD Castellón | 1:0 (1:0) | ||
| 19:00 | SD Eibar | - | Gimnàstic de Tarragona | 0:1 (0:1) | ||
| 19.02.2006 | 17:00 | Xerez CD | - | CD Numancia | 1:1 (0:0) | |
| 17:00 | UE Lleida | - | Racing Ferrol | 1:1 (1:1) | ||
| 17:00 | Polideportivo Ejido | - | Elche CF | 2:1 (0:1) | ||
| 17:00 | Levante UD | - | Real Murcia | 1:0 (1:0) | ||
| 17:00 | Real Valladolid | - | Recreativo Huelva | 0:1 (0:1) | ||
| 17:30 | CD Tenerife | - | Real Madrid Castilla | 0:1 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Recreativo Huelva | 25 | 13 | 8 | 4 | 35:20 | 15 | 47 |
| 2 |
|
Xerez CD | 25 | 12 | 9 | 4 | 41:26 | 15 | 45 |
| 3 |
|
Levante UD | 25 | 12 | 8 | 5 | 34:24 | 10 | 44 |
| 4 |
|
Lorca Deportiva | 25 | 12 | 7 | 6 | 36:21 | 15 | 43 |
| 5 |
|
Gimnàstic de Tarragona | 25 | 13 | 3 | 9 | 26:25 | 1 | 42 |
| 6 |
|
UD Almería | 25 | 11 | 6 | 8 | 30:23 | 7 | 39 |
| 7 |
|
Albacete | 25 | 10 | 6 | 9 | 26:32 | -6 | 36 |
| 8 |
|
Real Madrid Castilla | 25 | 10 | 5 | 10 | 34:28 | 6 | 35 |
| 9 |
|
Real Valladolid | 25 | 8 | 11 | 6 | 34:29 | 5 | 35 |
| 10 |
|
Ciudad de Murcia | 25 | 9 | 8 | 8 | 29:29 | 0 | 35 |
| 11 |
|
CD Numancia | 25 | 8 | 9 | 8 | 24:32 | -8 | 33 |
| 12 |
|
Sporting Gijón | 25 | 7 | 11 | 7 | 25:21 | 4 | 32 |
| 13 |
|
Real Murcia | 25 | 8 | 8 | 9 | 23:23 | 0 | 32 |
| 14 |
|
Elche CF | 25 | 8 | 7 | 10 | 31:37 | -6 | 31 |
| 15 |
|
Hércules CF | 25 | 7 | 9 | 9 | 26:30 | -4 | 30 |
| 16 |
|
CD Tenerife | 25 | 8 | 6 | 11 | 32:37 | -5 | 30 |
| 17 |
|
UE Lleida | 25 | 8 | 5 | 12 | 25:27 | -2 | 29 |
| 18 |
|
Polideportivo Ejido | 25 | 8 | 5 | 12 | 27:33 | -6 | 29 |
| 19 |
|
Racing Ferrol | 25 | 5 | 11 | 9 | 29:35 | -6 | 26 |
| 20 |
|
CD Castellón | 25 | 6 | 7 | 12 | 23:33 | -10 | 25 |
| 21 |
|
SD Eibar | 25 | 4 | 11 | 10 | 18:28 | -10 | 23 |
| 22 |
|
Atlético Malagueño | 25 | 4 | 8 | 13 | 17:32 | -15 | 20 |
