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| 18.03.2006 | 18:30 | CD Tenerife | - | Xerez CD | 3:1 (2:1) | |
| 18:30 | Ciudad de Murcia | - | Hércules CF | 1:0 (0:0) | ||
| 18:30 | UE Lleida | - | Real Murcia | 1:1 (0:0) | ||
| 18:30 | Elche CF | - | Albacete | 4:3 (2:1) | ||
| 18:30 | Polideportivo Ejido | - | Recreativo Huelva | 0:0 (0:0) | ||
| 19.03.2006 | 12:00 | Lorca Deportiva | - | Real Madrid Castilla | 2:1 (2:1) | |
| 17:00 | Real Valladolid | - | CD Castellón | 1:0 (0:0) | ||
| 17:00 | Racing Ferrol | - | Gimnàstic de Tarragona | 1:1 (0:0) | ||
| 17:30 | SD Eibar | - | UD Almería | 0:1 (0:1) | ||
| 18:00 | Levante UD | - | Atlético Malagueño | 2:1 (2:1) | ||
| 19:00 | Sporting Gijón | - | CD Numancia | 1:0 (1:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Recreativo Huelva | 29 | 14 | 10 | 5 | 40:23 | 17 | 52 |
| 2 |
|
Gimnàstic de Tarragona | 29 | 15 | 5 | 9 | 32:27 | 5 | 50 |
| 3 |
|
Xerez CD | 29 | 13 | 10 | 6 | 45:30 | 15 | 49 |
| 4 |
|
Lorca Deportiva | 29 | 14 | 7 | 8 | 41:27 | 14 | 49 |
| 5 |
|
Levante UD | 29 | 13 | 10 | 6 | 39:31 | 8 | 49 |
| 6 |
|
UD Almería | 29 | 14 | 6 | 9 | 35:25 | 10 | 48 |
| 7 |
|
Ciudad de Murcia | 29 | 11 | 9 | 9 | 32:31 | 1 | 42 |
| 8 |
|
CD Numancia | 29 | 11 | 9 | 9 | 28:33 | -5 | 42 |
| 9 |
|
Real Valladolid | 29 | 10 | 11 | 8 | 38:33 | 5 | 41 |
| 10 |
|
Real Madrid Castilla | 29 | 11 | 6 | 12 | 37:32 | 5 | 39 |
| 11 |
|
Sporting Gijón | 29 | 9 | 12 | 8 | 28:23 | 5 | 39 |
| 12 |
|
Real Murcia | 29 | 9 | 11 | 9 | 27:26 | 1 | 38 |
| 13 |
|
Elche CF | 29 | 10 | 8 | 11 | 36:41 | -5 | 38 |
| 14 |
|
Albacete | 29 | 10 | 7 | 12 | 31:41 | -10 | 37 |
| 15 |
|
UE Lleida | 29 | 9 | 7 | 13 | 28:30 | -2 | 34 |
| 16 |
|
Polideportivo Ejido | 29 | 9 | 7 | 13 | 29:35 | -6 | 34 |
| 17 |
|
CD Tenerife | 29 | 9 | 7 | 13 | 36:43 | -7 | 34 |
| 18 |
|
Hércules CF | 29 | 8 | 9 | 12 | 28:36 | -8 | 33 |
| 19 |
|
Racing Ferrol | 29 | 6 | 13 | 10 | 34:40 | -6 | 31 |
| 20 |
|
CD Castellón | 29 | 7 | 8 | 14 | 26:37 | -11 | 29 |
| 21 |
|
Atlético Malagueño | 29 | 6 | 9 | 14 | 23:37 | -14 | 27 |
| 22 |
|
SD Eibar | 29 | 4 | 13 | 12 | 19:31 | -12 | 25 |
