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| 06.05.2006 | 18:30 | CD Numancia | - | Elche CF | 3:1 (2:0) | |
| 18:30 | CD Castellón | - | Real Murcia | 2:1 (2:0) | ||
| 18:30 | UD Almería | - | Albacete | 1:2 (0:2) | ||
| 18:30 | CD Tenerife | - | Lorca Deportiva | 2:3 (0:0) | ||
| 19:00 | Sporting Gijón | - | SD Eibar | 1:1 (0:0) | ||
| 07.05.2006 | 12:00 | Real Madrid Castilla | - | Gimnàstic de Tarragona | 1:0 (1:0) | |
| 17:30 | Ciudad de Murcia | - | Levante UD | 2:1 (2:0) | ||
| 18:00 | Hércules CF | - | Polideportivo Ejido | 1:0 (0:0) | ||
| 18:00 | Real Valladolid | - | UE Lleida | 3:2 (0:1) | ||
| 18:30 | Xerez CD | - | Racing Ferrol | 2:0 (1:0) | ||
| 19:00 | Atlético Malagueño | - | Recreativo Huelva | 0:2 (0:2) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Recreativo Huelva | 36 | 19 | 11 | 6 | 54:25 | 29 | 68 |
| 2 |
|
Gimnàstic de Tarragona | 36 | 20 | 5 | 11 | 43:35 | 8 | 65 |
| 3 |
|
Lorca Deportiva | 36 | 17 | 9 | 10 | 52:36 | 16 | 60 |
| 4 |
|
Levante UD | 36 | 16 | 12 | 8 | 46:37 | 9 | 60 |
| 5 |
|
UD Almería | 36 | 17 | 7 | 12 | 45:33 | 12 | 58 |
| 6 |
|
Ciudad de Murcia | 36 | 16 | 10 | 10 | 43:37 | 6 | 58 |
| 7 |
|
Xerez CD | 36 | 15 | 12 | 9 | 52:40 | 12 | 57 |
| 8 |
|
CD Numancia | 36 | 16 | 9 | 11 | 41:41 | 0 | 57 |
| 9 |
|
Real Madrid Castilla | 36 | 15 | 7 | 14 | 44:35 | 9 | 52 |
| 10 |
|
Sporting Gijón | 36 | 11 | 16 | 9 | 37:29 | 8 | 49 |
| 11 |
|
Albacete | 36 | 13 | 9 | 14 | 37:50 | -13 | 48 |
| 12 |
|
Real Valladolid | 36 | 12 | 11 | 13 | 48:48 | 0 | 47 |
| 13 |
|
Polideportivo Ejido | 36 | 13 | 7 | 16 | 38:44 | -6 | 46 |
| 14 |
|
Hércules CF | 36 | 12 | 10 | 14 | 34:41 | -7 | 46 |
| 15 |
|
Real Murcia | 36 | 11 | 12 | 13 | 33:32 | 1 | 45 |
| 16 |
|
CD Castellón | 36 | 12 | 9 | 15 | 37:42 | -5 | 45 |
| 17 |
|
Elche CF | 36 | 12 | 9 | 15 | 44:52 | -8 | 45 |
| 18 |
|
CD Tenerife | 36 | 11 | 9 | 16 | 45:53 | -8 | 42 |
| 19 |
|
UE Lleida | 36 | 10 | 8 | 18 | 37:46 | -9 | 38 |
| 20 |
|
Racing Ferrol | 36 | 7 | 14 | 15 | 38:52 | -14 | 35 |
| 21 |
|
SD Eibar | 36 | 5 | 14 | 17 | 24:40 | -16 | 29 |
| 22 |
|
Atlético Malagueño | 36 | 6 | 10 | 20 | 29:53 | -24 | 28 |
