26.11.2021 16:00 Legon Cities - Aduana Stars 0:1 (0:1)
27.11.2021 16:00 WAFA - Great Olympics 1:0 (0:0)
28.11.2021 16:00 Bechem United - Dreams FC 3:1 (1:1)
16:00 Bibiani Gold Stars - Accra Lions 2:0 (0:0)
16:00 Eleven Wonders - Elmina Sharks 3:1 (0:0)
16:00 Karela United - Asante Kotoko 0:0 (0:0)
16:00 King Faisal - Medeama SC 0:0 (0:0)
16:00 Real Tamale United - Ashanti Gold 2:0 (1:0)
29.12.2021 16:00 Hearts of Oak - Berekum Chelsea 2:0
# Mannschaft Sp. S. U. N. Tore Dif. Pk.
1 Asante Kotoko, Ghana Asante Kotoko 5 4 1 0 8:1 7 13
2 King Faisal, Ghana King Faisal 5 3 1 1 6:2 4 10
3 Bechem United, Ghana Bechem United 5 3 0 2 10:5 5 9
4 Aduana Stars, Ghana Aduana Stars 5 2 2 1 9:6 3 8
5 Great Olympics, Ghana Great Olympics 5 2 2 1 8:6 2 8
6 Bibiani Gold Stars, Ghana Bibiani Gold Stars 5 2 1 2 5:4 1 7
7 Dreams FC, Ghana Dreams FC 5 2 1 2 11:11 0 7
8 Real Tamale United, Ghana Real Tamale United 5 2 1 2 8:9 -1 7
9 Ashanti Gold, Ghana Ashanti Gold 5 2 1 2 4:5 -1 7
10 Hearts of Oak, Ghana Hearts of Oak 5 1 3 1 4:4 0 6
11 Karela United, Ghana Karela United 5 1 3 1 4:5 -1 6
12 Medeama SC, Ghana Medeama SC 5 1 3 1 3:5 -2 6
13 Legon Cities, Ghana Legon Cities 5 1 2 2 5:6 -1 5
14 Eleven Wonders, Ghana Eleven Wonders 5 1 2 2 3:4 -1 5
15 WAFA, Ghana WAFA 5 1 2 2 4:6 -2 5
16 Berekum Chelsea, Ghana Berekum Chelsea 5 1 1 3 2:5 -3 4
17 Accra Lions, Ghana Accra Lions 5 1 1 3 5:10 -5 4
  Elmina Sharks, Ghana Elmina Sharks 5 1 1 3 5:10 -5 4
  Champions League
  Abstieg