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| 01.05.2010 | 15:00 | FSV Fernwald | - | TSG Wörsdorf | 3:1 | |
| 15:00 | 1. FC Schwalmstadt | - | FSV Frankfurt II | 1:2 | ||
| 15:00 | VfB Marburg | - | Viktoria Urberach | 3:2 | ||
| 15:00 | Germania Ober-Roden | - | Eintracht Stadtallendorf | 3:0 | ||
| 15:00 | SC Waldgirmes | - | OSC Vellmar | 1:1 | ||
| 15:00 | KSV Klein-Karben | - | SVA Bad Hersfeld | 5:1 | ||
| 15:00 | Viktoria Aschaffenburg | - | 1. FC Eschborn | 2:1 | ||
| 15:00 | Rot-Weiss Frankfurt | - | RSV Würges | 2:2 | ||
| 15:00 | Hünfelder SV | - | Kickers Offenbach II | 2:0 |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FSV Frankfurt II | 33 | 23 | 7 | 3 | 87:28 | 59 | 76 |
| 2 |
|
KSV Baunatal | 32 | 18 | 5 | 9 | 69:45 | 24 | 59 |
| 3 |
|
SC Waldgirmes | 32 | 15 | 13 | 4 | 76:53 | 23 | 58 |
| 4 |
|
Eintracht Stadtallendorf | 32 | 15 | 10 | 7 | 55:37 | 18 | 55 |
| 5 |
|
Kickers Offenbach II | 32 | 16 | 4 | 12 | 66:55 | 11 | 52 |
| 6 |
|
RSV Würges | 32 | 13 | 12 | 7 | 56:42 | 14 | 51 |
| 7 |
|
Rot-Weiss Frankfurt | 32 | 13 | 12 | 7 | 57:45 | 12 | 51 |
| 8 |
|
Hünfelder SV | 32 | 14 | 8 | 10 | 50:37 | 13 | 50 |
| 9 |
|
Viktoria Aschaffenburg | 32 | 13 | 10 | 9 | 48:45 | 3 | 49 |
| 10 |
|
1. FC Eschborn | 32 | 13 | 8 | 11 | 67:60 | 7 | 47 |
| 11 |
|
Viktoria Urberach | 33 | 12 | 10 | 11 | 60:57 | 3 | 46 |
| 12 |
|
VfB Marburg | 33 | 13 | 7 | 13 | 60:58 | 2 | 46 |
| 13 |
|
FSV Fernwald | 32 | 11 | 6 | 15 | 49:60 | -11 | 39 |
| 14 |
|
1. FC Schwalmstadt | 33 | 9 | 8 | 16 | 53:67 | -14 | 35 |
| 15 |
|
Germania Ober-Roden | 32 | 10 | 5 | 17 | 46:63 | -17 | 35 |
| 16 |
|
KSV Klein-Karben | 32 | 8 | 6 | 18 | 55:73 | -18 | 30 |
| 17 |
|
OSC Vellmar | 32 | 7 | 7 | 18 | 43:69 | -26 | 28 |
| 18 |
|
TSG Wörsdorf | 32 | 5 | 6 | 21 | 41:76 | -35 | 21 |
| 19 |
|
SVA Bad Hersfeld | 32 | 4 | 4 | 24 | 44:112 | -68 | 16 |
| Aufstieg | |
| Relegation | |
| Abstieg |
