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| 15.05.2010 | 14:00 | KSV Baunatal | - | FSV Fernwald | 1:1 | |
| 15:00 | Viktoria Urberach | - | FSV Frankfurt II | 3:6 | ||
| 15:00 | SC Waldgirmes | - | Germania Ober-Roden | 2:0 | ||
| 15:00 | KSV Klein-Karben | - | Eintracht Stadtallendorf | 4:2 | ||
| 15:00 | Viktoria Aschaffenburg | - | OSC Vellmar | 1:2 | ||
| 15:00 | Rot-Weiss Frankfurt | - | SVA Bad Hersfeld | 7:0 | ||
| 15:00 | TSG Wörsdorf | - | 1. FC Eschborn | 0:3 | ||
| 15:00 | Hünfelder SV | - | RSV Würges | 0:3 | ||
| 15:00 | VfB Marburg | - | Kickers Offenbach II | 1:2 |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FSV Frankfurt II | 35 | 24 | 8 | 3 | 94:32 | 62 | 80 |
| 2 |
|
SC Waldgirmes | 34 | 17 | 13 | 4 | 79:53 | 26 | 64 |
| 3 |
|
KSV Baunatal | 34 | 18 | 6 | 10 | 70:51 | 19 | 60 |
| 4 |
|
Kickers Offenbach II | 34 | 18 | 4 | 12 | 73:56 | 17 | 58 |
| 5 |
|
RSV Würges | 34 | 15 | 12 | 7 | 60:42 | 18 | 57 |
| 6 |
|
Eintracht Stadtallendorf | 34 | 15 | 10 | 9 | 57:42 | 15 | 55 |
| 7 |
|
Rot-Weiss Frankfurt | 34 | 14 | 12 | 8 | 64:50 | 14 | 54 |
| 8 |
|
1. FC Eschborn | 34 | 15 | 8 | 11 | 75:60 | 15 | 53 |
| 9 |
|
Hünfelder SV | 34 | 15 | 8 | 11 | 54:43 | 11 | 53 |
| 10 |
|
Viktoria Aschaffenburg | 34 | 14 | 10 | 10 | 52:47 | 5 | 52 |
| 11 |
|
Viktoria Urberach | 35 | 13 | 10 | 12 | 65:63 | 2 | 49 |
| 12 |
|
VfB Marburg | 34 | 13 | 7 | 14 | 61:60 | 1 | 46 |
| 13 |
|
FSV Fernwald | 34 | 11 | 7 | 16 | 53:65 | -12 | 40 |
| 14 |
|
Germania Ober-Roden | 34 | 10 | 6 | 18 | 47:66 | -19 | 36 |
| 15 |
|
1. FC Schwalmstadt | 34 | 9 | 8 | 17 | 53:69 | -16 | 35 |
| 16 |
|
OSC Vellmar | 34 | 9 | 7 | 18 | 49:73 | -24 | 34 |
| 17 |
|
KSV Klein-Karben | 34 | 9 | 6 | 19 | 62:79 | -17 | 33 |
| 18 |
|
TSG Wörsdorf | 34 | 5 | 6 | 23 | 41:80 | -39 | 21 |
| 19 |
|
SVA Bad Hersfeld | 34 | 4 | 4 | 26 | 44:122 | -78 | 16 |
| Aufstieg | |
| Relegation | |
| Abstieg |
