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| 06.11.2021 | 14:00 | Eintracht Stadtallendorf | - | SV Steinbach | 2:0 (2:0) | |
| 14:30 | Hünfelder SV | - | Bayern Alzenau | 0:4 (0:1) | ||
| 14:30 | SV Buchonia Flieden | - | FC Hanau 93 | 2:1 (1:0) | ||
| 14:30 | KSV Baunatal | - | SG Barockstadt Fulda-Lehnerz | 3:3 (2:1) | ||
| 14:30 | FSV Fernwald | - | 1. FC 06 Erlensee | 1:1 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SG Barockstadt Fulda-Lehnerz | 15 | 11 | 3 | 1 | 36:14 | 22 | 36 |
| 2 |
|
Eintracht Stadtallendorf | 15 | 10 | 4 | 1 | 30:10 | 20 | 34 |
| 3 |
|
1. FC 06 Erlensee | 16 | 10 | 4 | 2 | 35:16 | 19 | 34 |
| 4 |
|
Bayern Alzenau | 15 | 4 | 7 | 4 | 24:24 | 0 | 19 |
| 5 |
|
Hünfelder SV | 16 | 4 | 7 | 5 | 21:22 | -1 | 19 |
| 6 |
|
FSV Fernwald | 15 | 3 | 9 | 3 | 30:28 | 2 | 18 |
| 7 |
|
KSV Baunatal | 16 | 4 | 5 | 7 | 23:27 | -4 | 17 |
| 8 |
|
FC Hanau 93 | 15 | 4 | 4 | 7 | 21:26 | -5 | 16 |
| 9 |
|
SV 1910 Neuhof | 15 | 3 | 4 | 8 | 18:25 | -7 | 13 |
| 10 |
|
SV Buchonia Flieden | 16 | 3 | 4 | 9 | 16:40 | -24 | 13 |
| 11 |
|
SV Steinbach | 16 | 2 | 3 | 11 | 15:37 | -22 | 9 |
| Playoffs | |
| Relegation |
