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| H | Gallos Blancos (old) | - | Deportivo Guadalajara | 2:1 (1:0) | ||
| R | Deportivo Guadalajara | - | Gallos Blancos (old) | 0:0 (0:0) | ||
| H: 20.11.2011 00:00 | R: 27.11.2011 02:00 | Sieger: Gallos Blancos (old) | ||||
| H | Monarcas Morelia | - | Cruz Azul | 2:1 (0:1) | ||
| R | Cruz Azul | - | Monarcas Morelia | 1:2 (1:2) | ||
| H: 20.11.2011 02:00 | R: 27.11.2011 00:00 | Sieger: Monarcas Morelia | ||||
| H | Jaguares Chiapas | - | Santos Laguna | 2:2 (0:2) | ||
| R | Santos Laguna | - | Jaguares Chiapas | 2:1 (1:0) | ||
| H: 20.11.2011 23:00 | R: 28.11.2011 00:00 | Sieger: Santos Laguna | ||||
| H | CF Pachuca | - | UANL Tigres | 0:1 (0:1) | ||
| R | UANL Tigres | - | CF Pachuca | 3:0 (3:0) | ||
| H: 21.11.2011 01:00 | R: 28.11.2011 02:00 | Sieger: UANL Tigres | ||||
