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| H | UANL Tigres | - | CF Monterrey | 1:1 (0:1) | ||
| R | CF Monterrey | - | UANL Tigres | 0:1 (0:0) | ||
| H: 18.05.2023 05:00 | R: 21.05.2023 03:06 | Sieger: UANL Tigres | ||||
| H | Deportivo Guadalajara | - | CF América | 0:1 (0:0) | ||
| R | CF América | - | Deportivo Guadalajara | 1:3 (0:1) | ||
| H: 19.05.2023 04:10 | R: 22.05.2023 04:00 | Sieger: Deportivo Guadalajara | ||||
