 |
 |
|
| 23.10.2021 | 16:00 | UANL Tigres | - | CF Monterrey | 0:0 (0:0) | |
| 16:00 | Cruz Azul | - | CF América | 2:2 (1:1) | ||
| 16:00 | Gallos Blancos | - | Pumas UNAM | 0:1 (0:0) | ||
| 16:00 | Atlas Guadalajara | - | Club León | 0:0 (0:0) | ||
| 17:00 | FC Juárez | - | Deportivo Toluca | 0:1 (0:0) | ||
| 19:00 | Club Tijuana | - | CF Pachuca | 0:1 (0:0) | ||
| 19:00 | Club Necaxa | - | Atlético San Luis | 4:0 (2:0) | ||
| 23:00 | Deportivo Guadalajara | - | Mazatlán FC | 5:3 (2:2) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Deportivo Guadalajara | 12 | 8 | 3 | 1 | 36:14 | 22 | 27 |
| 2 |
|
Pumas UNAM | 12 | 8 | 2 | 2 | 21:10 | 11 | 26 |
| 3 |
|
Deportivo Toluca | 13 | 7 | 5 | 1 | 20:13 | 7 | 26 |
| 4 |
|
Santos Laguna | 12 | 7 | 4 | 1 | 27:13 | 14 | 25 |
| 5 |
|
Cruz Azul | 13 | 7 | 3 | 3 | 18:13 | 5 | 24 |
| 6 |
|
CF Pachuca | 13 | 7 | 3 | 3 | 16:11 | 5 | 24 |
| 7 |
|
UANL Tigres | 13 | 6 | 3 | 4 | 21:16 | 5 | 21 |
| 8 |
|
Club Necaxa | 12 | 6 | 2 | 4 | 20:13 | 7 | 20 |
| 9 |
|
CF Monterrey | 13 | 5 | 4 | 4 | 20:17 | 3 | 19 |
| 10 |
|
Atlas Guadalajara | 12 | 5 | 1 | 6 | 28:25 | 3 | 16 |
| 11 |
|
Club Tijuana | 12 | 5 | 1 | 6 | 14:18 | -4 | 16 |
| 12 |
|
Club León | 12 | 4 | 3 | 5 | 18:19 | -1 | 15 |
| 13 |
|
CF América | 12 | 4 | 1 | 7 | 18:18 | 0 | 13 |
| 14 |
|
Puebla FC | 12 | 3 | 3 | 6 | 19:23 | -4 | 12 |
| 15 |
|
Gallos Blancos | 13 | 2 | 4 | 7 | 14:18 | -4 | 10 |
| 16 |
|
Mazatlán FC | 13 | 3 | 1 | 9 | 20:42 | -22 | 10 |
| 17 |
|
FC Juárez | 12 | 1 | 2 | 9 | 8:24 | -16 | 5 |
| 18 |
|
Atlético San Luis | 13 | 1 | 1 | 11 | 9:40 | -31 | 4 |
| Playoffs |
