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| H | Monarcas Morelia | - | Pumas UNAM | 0:2 (0:1) | ||
| R | Pumas UNAM | - | Monarcas Morelia | 4:1 (2:1) | ||
| H: 15.05.2019 17:00 | R: 18.05.2019 19:00 | Sieger: Pumas UNAM | ||||
| H | Atlas Guadalajara | - | Santos Laguna | 1:1 (1:1) | ||
| R | Santos Laguna | - | Atlas Guadalajara | 2:4 (1:1) | ||
| H: 16.05.2019 17:00 | R: 19.05.2019 16:00 | Sieger: Atlas Guadalajara | ||||
