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| H | Atlas Guadalajara | - | CF Monterrey | 0:0 (0:0) | ||
| R | CF Monterrey | - | Atlas Guadalajara | 1:1 (0:0) | ||
| H: 25.11.2020 16:00 | R: 28.11.2020 16:00 | Sieger: Atlas Guadalajara | ||||
| H | Cruz Azul | - | Deportivo Guadalajara | 0:1 (0:0) | ||
| R | Deportivo Guadalajara | - | Cruz Azul | 5:1 (1:1) | ||
| H: 26.11.2020 18:00 | R: 29.11.2020 16:00 | Sieger: Deportivo Guadalajara | ||||
