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| 05.11.2021 | 19:00 | FC Nöttingen | - | SV Oberachern | 0:2 (0:1) | |
| 06.11.2021 | 14:00 | Göppinger SV | - | FC-Astoria Walldorf II | 2:0 (1:0) | |
| 14:00 | Neckarsulmer Sport-Union | - | SV Linx | 1:2 (1:0) | ||
| 14:00 | TSV Ilshofen | - | TSG Backnang | 0:2 (0:2) | ||
| 14:30 | 1. FC Bruchsal | - | SSV Reutlingen | 1:2 (0:1) | ||
| 14:30 | Freiburger FC | - | FV Ravensburg | 1:3 (0:2) | ||
| 14:30 | FSV 08 Bietigheim-Bissingen | - | SGV Freiberg | 0:2 (0:1) | ||
| 07.11.2021 | 14:30 | 1. FC Rielasingen-Arlen | - | Sportfreunde Dorfmerkingen | 3:1 (1:0) | |
| 14:30 | FV Lörrach-Brombach | - | Stuttgarter Kickers | 0:3 (0:0) | ||
| 24.11.2021 | 19:00 | 1. CfR Pforzheim | - | FC 08 Villingen | 1:4 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SGV Freiberg | 16 | 11 | 4 | 1 | 53:14 | 39 | 37 |
| 2 |
|
Stuttgarter Kickers | 16 | 11 | 2 | 3 | 33:8 | 25 | 35 |
| 3 |
|
TSG Backnang | 16 | 10 | 1 | 5 | 35:21 | 14 | 31 |
| 4 |
|
FC 08 Villingen | 16 | 9 | 2 | 5 | 31:19 | 12 | 29 |
| 5 |
|
Göppinger SV | 16 | 8 | 4 | 4 | 27:23 | 4 | 28 |
| 6 |
|
1. FC Rielasingen-Arlen | 16 | 8 | 4 | 4 | 21:17 | 4 | 28 |
| 7 |
|
FSV 08 Bietigheim-Bissingen | 16 | 8 | 3 | 5 | 33:17 | 16 | 27 |
| 8 |
|
FC-Astoria Walldorf II | 16 | 8 | 2 | 6 | 23:22 | 1 | 26 |
| 9 |
|
SSV Reutlingen | 16 | 7 | 4 | 5 | 25:20 | 5 | 25 |
| 10 |
|
FV Ravensburg | 16 | 6 | 6 | 4 | 35:25 | 10 | 24 |
| 11 |
|
FC Nöttingen | 16 | 7 | 2 | 7 | 32:26 | 6 | 23 |
| 12 |
|
1. CfR Pforzheim | 16 | 7 | 2 | 7 | 23:24 | -1 | 23 |
| 13 |
|
SV Oberachern | 16 | 7 | 1 | 8 | 25:30 | -5 | 22 |
| 14 |
|
Neckarsulmer Sport-Union | 16 | 5 | 4 | 7 | 23:29 | -6 | 19 |
| 15 |
|
SV Linx | 16 | 5 | 4 | 7 | 15:33 | -18 | 19 |
| 16 |
|
Sportfreunde Dorfmerkingen | 16 | 4 | 4 | 8 | 19:35 | -16 | 16 |
| 17 |
|
Freiburger FC | 16 | 3 | 4 | 9 | 17:29 | -12 | 13 |
| 18 |
|
1. FC Bruchsal | 16 | 3 | 2 | 11 | 15:39 | -24 | 11 |
| 19 |
|
TSV Ilshofen | 16 | 2 | 2 | 12 | 15:43 | -28 | 8 |
| 20 |
|
FV Lörrach-Brombach | 16 | 1 | 3 | 12 | 9:35 | -26 | 6 |
| Aufstieg | |
| Relegation | |
| Abstieg |
