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| 09.03.2022 | 18:00 | Sportfreunde Dorfmerkingen | - | FC-Astoria Walldorf II | 3:2 (1:2) | |
| 19:00 | 1. FC Bruchsal | - | 1. FC Rielasingen-Arlen | 1:2 (0:2) | ||
| 19:00 | FC Nöttingen | - | TSG Backnang | 3:2 (0:2) | ||
| 19:00 | Göppinger SV | - | FC 08 Villingen | 2:1 (1:0) | ||
| 19:00 | Stuttgarter Kickers | - | SGV Freiberg | 1:2 (0:1) | ||
| 19:00 | TSV Ilshofen | - | Neckarsulmer Sport-Union | 3:0 (1:0) | ||
| 19:00 | Freiburger FC | - | 1. CfR Pforzheim | 4:2 (4:1) | ||
| 19:00 | FSV 08 Bietigheim-Bissingen | - | SV Linx | 3:3 (3:0) | ||
| 19:00 | SSV Reutlingen | - | SV Oberachern | 0:1 (0:0) | ||
| 19:00 | FV Lörrach-Brombach | - | FV Ravensburg | 3:5 (2:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SGV Freiberg | 21 | 16 | 4 | 1 | 70:16 | 54 | 52 |
| 2 |
|
Stuttgarter Kickers | 21 | 15 | 2 | 4 | 47:15 | 32 | 47 |
| 3 |
|
Göppinger SV | 21 | 12 | 4 | 5 | 38:29 | 9 | 40 |
| 4 |
|
TSG Backnang | 21 | 11 | 2 | 8 | 47:32 | 15 | 35 |
| 5 |
|
1. CfR Pforzheim | 21 | 11 | 2 | 8 | 36:30 | 6 | 35 |
| 6 |
|
FC 08 Villingen | 21 | 10 | 3 | 8 | 36:27 | 9 | 33 |
| 7 |
|
FV Ravensburg | 21 | 8 | 8 | 5 | 45:34 | 11 | 32 |
| 8 |
|
FC Nöttingen | 21 | 10 | 2 | 9 | 42:40 | 2 | 32 |
| 9 |
|
1. FC Rielasingen-Arlen | 21 | 9 | 5 | 7 | 26:26 | 0 | 32 |
| 10 |
|
FSV 08 Bietigheim-Bissingen | 21 | 8 | 7 | 6 | 43:28 | 15 | 31 |
| 11 |
|
SV Oberachern | 21 | 10 | 1 | 10 | 39:39 | 0 | 31 |
| 12 |
|
SSV Reutlingen | 21 | 8 | 5 | 8 | 31:29 | 2 | 29 |
| 13 |
|
Neckarsulmer Sport-Union | 21 | 8 | 4 | 9 | 27:34 | -7 | 28 |
| 14 |
|
FC-Astoria Walldorf II | 21 | 8 | 3 | 10 | 31:40 | -9 | 27 |
| 15 |
|
SV Linx | 21 | 7 | 5 | 9 | 25:46 | -21 | 26 |
| 16 |
|
Freiburger FC | 21 | 6 | 4 | 11 | 29:36 | -7 | 22 |
| 17 |
|
Sportfreunde Dorfmerkingen | 21 | 5 | 4 | 12 | 24:49 | -25 | 19 |
| 18 |
|
1. FC Bruchsal | 21 | 5 | 3 | 13 | 24:49 | -25 | 18 |
| 19 |
|
TSV Ilshofen | 21 | 4 | 4 | 13 | 24:48 | -24 | 16 |
| 20 |
|
FV Lörrach-Brombach | 21 | 1 | 4 | 16 | 16:53 | -37 | 7 |
| Aufstieg | |
| Relegation | |
| Abstieg |
