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| 25.09.2021 | 20:00 | SV Deutz 05 | - | 1. FC Düren | 0:4 (0:2) | |
| 26.09.2021 | 15:00 | BC Viktoria Glesch-Paffendorf | - | FC Hürth | 1:2 (0:2) | |
| 15:00 | Spvg Wesseling-Urfeld | - | Borussia Freialdenhoven | 1:2 (1:1) | ||
| 15:00 | Viktoria Arnoldsweiler | - | SV Bergisch Gladbach 09 | 0:3 (0:1) | ||
| 15:00 | VfL Alfter | - | Fortuna Köln II | 2:0 (1:0) | ||
| 15:00 | SV Breinig | - | SpVg Frechen 20 | 0:4 (0:1) | ||
| 15:00 | SV 1914 Eilendorf | - | VfL 08 Vichttal | 1:2 (0:1) | ||
| 15:30 | FC Pesch 1956 | - | FC Hennef 05 | 0:2 (0:1) | ||
| 15:30 | Siegburger SV 04 | - | Blau-Weiß Friesdorf | 1:1 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FC Düren | 8 | 7 | 1 | 0 | 28:4 | 24 | 22 |
| 2 |
|
FC Hennef 05 | 8 | 6 | 2 | 0 | 19:3 | 16 | 20 |
| 3 |
|
SpVg Frechen 20 | 8 | 6 | 0 | 2 | 22:7 | 15 | 18 |
| 4 |
|
Borussia Freialdenhoven | 8 | 6 | 0 | 2 | 18:9 | 9 | 18 |
| 5 |
|
SV Bergisch Gladbach 09 | 8 | 4 | 3 | 1 | 20:7 | 13 | 15 |
| 6 |
|
FC Hürth | 8 | 5 | 0 | 3 | 11:13 | -2 | 15 |
| 7 |
|
VfL Alfter | 8 | 4 | 2 | 2 | 13:11 | 2 | 14 |
| 8 |
|
BC Viktoria Glesch-Paffendorf | 8 | 4 | 1 | 3 | 12:10 | 2 | 13 |
| 9 |
|
VfL 08 Vichttal | 8 | 4 | 1 | 3 | 14:16 | -2 | 13 |
| 10 |
|
FC Pesch 1956 | 8 | 3 | 3 | 2 | 18:8 | 10 | 12 |
| 11 |
|
Siegburger SV 04 | 8 | 3 | 3 | 2 | 11:9 | 2 | 12 |
| 12 |
|
Viktoria Arnoldsweiler | 8 | 3 | 1 | 4 | 15:15 | 0 | 10 |
| 13 |
|
SV Deutz 05 | 8 | 2 | 1 | 5 | 9:20 | -11 | 7 |
| 14 |
|
Blau-Weiß Friesdorf | 8 | 1 | 3 | 4 | 8:15 | -7 | 6 |
| 15 |
|
Fortuna Köln II | 8 | 1 | 1 | 6 | 7:17 | -10 | 4 |
| 16 |
|
SV 1914 Eilendorf | 8 | 1 | 0 | 7 | 3:22 | -19 | 3 |
| 17 |
|
Spvg Wesseling-Urfeld | 8 | 1 | 0 | 7 | 8:28 | -20 | 3 |
| 18 |
|
SV Breinig | 8 | 0 | 0 | 8 | 3:25 | -22 | 0 |
| Playoffs | |
| Abstieg |
