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| 04.11.2022 | 19:30 | ASC 09 Dortmund | - | TSG Sprockhövel | 2:1 (2:0) | |
| 20:00 | SV Schermbeck | - | SC Paderborn 07 II | 3:2 (3:0) | ||
| 06.11.2022 | 14:30 | Sportfreunde Siegen | - | Delbrücker SC | 4:2 (2:1) | |
| 14:30 | Preußen Münster II | - | TuS Ennepetal | 2:0 (0:0) | ||
| 14:30 | 1. FC Gievenbeck | - | Westfalia Rhynern | 0:5 (0:1) | ||
| 14:30 | FC Gütersloh | - | FCE Rheine | 0:1 (0:0) | ||
| 14:30 | SpVgg Vreden | - | Viktoria Clarholz | 0:2 (0:1) | ||
| 14:30 | TuS Bövinghausen | - | TuS Erndtebrück | 4:1 (4:0) | ||
| 15:00 | SG Finnentrop/Bamenohl | - | Sportfreunde Lotte | 3:0 (2:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
TuS Bövinghausen | 13 | 9 | 2 | 2 | 32:20 | 12 | 29 |
| 2 |
|
Preußen Münster II | 13 | 8 | 4 | 1 | 34:14 | 20 | 28 |
| 3 |
|
Westfalia Rhynern | 13 | 8 | 4 | 1 | 24:9 | 15 | 28 |
| 4 |
|
Viktoria Clarholz | 13 | 8 | 2 | 3 | 24:16 | 8 | 26 |
| 5 |
|
FC Gütersloh | 13 | 8 | 1 | 4 | 26:18 | 8 | 25 |
| 6 |
|
SC Paderborn 07 II | 13 | 7 | 3 | 3 | 21:11 | 10 | 24 |
| 7 |
|
FCE Rheine | 13 | 6 | 2 | 5 | 21:19 | 2 | 20 |
| 8 |
|
ASC 09 Dortmund | 13 | 6 | 1 | 6 | 15:15 | 0 | 19 |
| 9 |
|
SV Schermbeck | 13 | 5 | 3 | 5 | 19:19 | 0 | 18 |
| 10 |
|
SG Finnentrop/Bamenohl | 13 | 5 | 1 | 7 | 27:29 | -2 | 16 |
| 11 |
|
SpVgg Vreden | 13 | 4 | 4 | 5 | 20:27 | -7 | 16 |
| 12 |
|
1. FC Gievenbeck | 13 | 4 | 3 | 6 | 20:23 | -3 | 15 |
| 13 |
|
Sportfreunde Lotte | 13 | 4 | 2 | 7 | 21:22 | -1 | 14 |
| 14 |
|
Sportfreunde Siegen | 13 | 3 | 3 | 7 | 17:20 | -3 | 12 |
| 15 |
|
TSG Sprockhövel | 13 | 3 | 2 | 8 | 21:32 | -11 | 11 |
| 16 |
|
TuS Erndtebrück | 13 | 3 | 2 | 8 | 18:38 | -20 | 11 |
| 17 |
|
Delbrücker SC | 13 | 2 | 4 | 7 | 19:28 | -9 | 10 |
| 18 |
|
TuS Ennepetal | 13 | 2 | 1 | 10 | 9:28 | -19 | 7 |
| Aufstieg | |
| Aufstieg | |
| Abstieg |
