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| 23.04.2022 | 02:00 | Veraguas United | - | Herrera FC | 2:2 (1:2) | |
| 03:00 | Plaza Amador | - | Sporting San Miguelito | 1:1 (1:0) | ||
| 22:00 | Árabe Unido | - | Deportivo del Este | 2:1 (2:0) | ||
| 24.04.2022 | 00:00 | Atlético Chiriquí | - | UD Universitario | 1:0 (1:0) | |
| 02:00 | Alianza | - | Tauro FC | 0:1 (0:0) | ||
| 03:00 | Independiente de La Chorrera | - | San Francisco FC | 1:4 (1:2) |
| 1 | |||||||||
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Alianza | 13 | 7 | 4 | 2 | 13:5 | 8 | 25 |
| 2 |
|
Sporting San Miguelito | 13 | 6 | 6 | 1 | 19:11 | 8 | 24 |
| 3 |
|
Tauro FC | 13 | 7 | 3 | 3 | 17:9 | 8 | 24 |
| 4 |
|
Plaza Amador | 13 | 4 | 7 | 2 | 23:18 | 5 | 19 |
| 5 |
|
Deportivo del Este | 13 | 2 | 7 | 4 | 13:17 | -4 | 13 |
| 6 |
|
Árabe Unido | 13 | 1 | 7 | 5 | 4:9 | -5 | 10 |
| 2 | |||||||||
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Atlético Chiriquí | 13 | 7 | 2 | 4 | 17:17 | 0 | 23 |
| 2 |
|
Independiente de La Chorrera | 13 | 6 | 2 | 5 | 15:15 | 0 | 20 |
| 3 |
|
Herrera FC | 13 | 3 | 8 | 2 | 15:12 | 3 | 17 |
| 4 |
|
San Francisco FC | 13 | 3 | 4 | 6 | 12:11 | 1 | 13 |
| 5 |
|
Veraguas United | 13 | 1 | 6 | 6 | 11:22 | -11 | 9 |
| 6 |
|
UD Universitario | 13 | 2 | 2 | 9 | 8:21 | -13 | 8 |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Playoffs |
