| H | Sportivo Ameliano | - | Sportivo Luqueño | 3:2 (1:1) | ||
| R | Sportivo Luqueño | - | Sportivo Ameliano | 1:1 (0:1) | ||
| H: 07.12.2021 23:30 | R: 11.12.2021 23:30 | Sieger: Sportivo Ameliano | ||||
| H | Sportivo Ameliano | - | Sportivo Luqueño | 3:2 (1:1) | ||
| R | Sportivo Luqueño | - | Sportivo Ameliano | 1:1 (0:1) | ||
| H: 07.12.2021 23:30 | R: 11.12.2021 23:30 | Sieger: Sportivo Ameliano | ||||
