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| 29.10.2021 | 18:00 | KS Cracovia | - | Radomiak Radom | 1:2 (0:1) | |
| 20:30 | FKS Stal Mielec | - | Lech Poznań | 0:0 (0:0) | ||
| 30.10.2021 | 12:30 | Bruk-Bet Termalica Nieciecza | - | Śląsk Wrocław | 4:3 (1:1) | |
| 15:00 | Warta Poznań | - | Lechia Gdańsk | 0:2 (0:0) | ||
| 17:30 | Górnik Zabrze | - | Zagłębie Lubin | 0:0 (0:0) | ||
| 20:00 | Jagiellonia Białystok | - | Piast Gliwice | 3:3 (0:2) | ||
| 31.10.2021 | 12:30 | Wisła Płock | - | Wisła Kraków | 2:0 (1:0) | |
| 15:00 | Górnik Łęczna | - | Raków Częstochowa | 0:0 (0:0) | ||
| 17:30 | Legia Warszawa | - | Pogoń Szczecin | 0:2 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Lech Poznań | 13 | 8 | 4 | 1 | 27:7 | 20 | 28 |
| 2 |
|
Lechia Gdańsk | 13 | 7 | 5 | 1 | 23:10 | 13 | 26 |
| 3 |
|
Pogoń Szczecin | 13 | 7 | 4 | 2 | 22:10 | 12 | 25 |
| 4 |
|
Raków Częstochowa | 13 | 7 | 4 | 2 | 25:18 | 7 | 25 |
| 5 |
|
Śląsk Wrocław | 13 | 5 | 5 | 3 | 23:18 | 5 | 20 |
| 6 |
|
Radomiak Radom | 13 | 4 | 7 | 2 | 17:13 | 4 | 19 |
| 7 |
|
Piast Gliwice | 13 | 5 | 3 | 5 | 21:19 | 2 | 18 |
| 8 |
|
Górnik Zabrze | 13 | 5 | 3 | 5 | 16:17 | -1 | 18 |
| 9 |
|
KS Cracovia | 13 | 4 | 5 | 4 | 20:21 | -1 | 17 |
| 10 |
|
Jagiellonia Białystok | 13 | 4 | 5 | 4 | 16:19 | -3 | 17 |
| 11 |
|
FKS Stal Mielec | 13 | 4 | 5 | 4 | 15:18 | -3 | 17 |
| 12 |
|
Zagłębie Lubin | 13 | 5 | 2 | 6 | 14:22 | -8 | 17 |
| 13 |
|
Wisła Płock | 13 | 5 | 1 | 7 | 21:21 | 0 | 16 |
| 14 |
|
Legia Warszawa | 13 | 5 | 0 | 8 | 19:20 | -1 | 15 |
| 15 |
|
Wisła Kraków | 13 | 4 | 2 | 7 | 14:23 | -9 | 14 |
| 16 |
|
Bruk-Bet Termalica Nieciecza | 13 | 2 | 4 | 7 | 17:25 | -8 | 10 |
| 17 |
|
Warta Poznań | 13 | 1 | 5 | 7 | 8:17 | -9 | 8 |
| 18 |
|
Górnik Łęczna | 13 | 1 | 4 | 8 | 10:30 | -20 | 7 |
| Champions League Quali. | |
| Europa Conference League Quali. | |
| Abstieg |
