 |
 |
|
| 29.01.2022 | 16:00 | SL Benfica | - | CD Nacional | 4:0 (2:0) | |
| 16:00 | Os Belenenses | - | Amora FC | 4:1 (1:1) | ||
| 16:00 | UD Vilafranquense | - | FC Alverca | 1:1 (1:0) | ||
| 16:00 | Académica de Coimbra | - | Sporting CP | 0:2 (0:0) | ||
| 16:00 | SG Sacavenense | - | Vitória Setúbal | 2:3 (0:1) | ||
| 16:00 | União Leiria | - | GD Estoril | 5:1 (2:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SL Benfica | 22 | 16 | 5 | 1 | 78:15 | 63 | 53 |
| 2 |
|
Sporting CP | 22 | 14 | 7 | 1 | 60:14 | 46 | 49 |
| 3 |
|
FC Alverca | 22 | 12 | 4 | 6 | 45:23 | 22 | 40 |
| 4 |
|
GD Estoril | 22 | 10 | 8 | 4 | 43:27 | 16 | 38 |
| 5 |
|
Vitória Setúbal | 22 | 9 | 8 | 5 | 38:37 | 1 | 35 |
| 6 |
|
Os Belenenses | 22 | 7 | 8 | 7 | 24:29 | -5 | 29 |
| 7 |
|
CD Nacional | 22 | 7 | 6 | 9 | 26:34 | -8 | 27 |
| 8 |
|
Académica de Coimbra | 22 | 6 | 6 | 10 | 31:37 | -6 | 24 |
| 9 |
|
UD Vilafranquense | 22 | 4 | 8 | 10 | 20:51 | -31 | 20 |
| 10 |
|
União Leiria | 22 | 5 | 4 | 13 | 24:51 | -27 | 19 |
| 11 |
|
SG Sacavenense | 22 | 3 | 4 | 15 | 21:57 | -36 | 13 |
| 12 |
|
Amora FC | 22 | 3 | 4 | 15 | 16:51 | -35 | 13 |
| Playoffs | |
| Relegation |
