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| 13.04.2006 | 19:00 | SV 07 Elversberg | - | SV Darmstadt 98 | 0:3 (0:2) | |
| 19:00 | Stuttgarter Kickers | - | FC Augsburg | 1:2 (1:0) | ||
| 19:00 | TSG Hoffenheim | - | TuS Koblenz | 1:2 (1:1) | ||
| 19:00 | Eintracht Trier | - | 1. FC Kaiserslautern II | 2:1 (2:0) | ||
| 19:00 | Bayern München II | - | SpVgg Bayreuth | 1:3 (1:2) | ||
| 15.04.2006 | 14:30 | Jahn Regensburg | - | Karlsruher SC II | 2:0 (2:0) | |
| 14:30 | SV Wehen-Taunusstein | - | VfB Stuttgart II | 1:2 (0:0) | ||
| 14:30 | VfR Aalen | - | TSV 1860 München II | 0:2 (0:1) | ||
| 14:30 | SC Pfullendorf | - | 1. FC Eschborn | 2:0 (1:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Augsburg | 28 | 19 | 6 | 3 | 58:22 | 36 | 63 |
| 2 |
|
TuS Koblenz | 28 | 14 | 10 | 4 | 42:26 | 16 | 52 |
| 3 |
|
TSG Hoffenheim | 28 | 14 | 5 | 9 | 39:27 | 12 | 47 |
| 4 |
|
VfB Stuttgart II | 28 | 13 | 8 | 7 | 47:39 | 8 | 47 |
| 5 |
|
SV Darmstadt 98 | 28 | 13 | 6 | 9 | 46:36 | 10 | 45 |
| 6 |
|
SpVgg Bayreuth | 28 | 11 | 10 | 7 | 44:38 | 6 | 43 |
| 7 |
|
VfR Aalen | 28 | 12 | 6 | 10 | 35:29 | 6 | 42 |
| 8 |
|
SV Wehen-Taunusstein | 28 | 12 | 5 | 11 | 50:41 | 9 | 41 |
| 9 |
|
Stuttgarter Kickers | 28 | 11 | 8 | 9 | 40:33 | 7 | 41 |
| 10 |
|
Karlsruher SC II | 28 | 12 | 5 | 11 | 36:36 | 0 | 41 |
| 11 |
|
SV 07 Elversberg | 28 | 9 | 9 | 10 | 28:33 | -5 | 36 |
| 12 |
|
TSV 1860 München II | 28 | 8 | 9 | 11 | 34:42 | -8 | 33 |
| 13 |
|
1. FC Kaiserslautern II | 28 | 9 | 4 | 15 | 29:35 | -6 | 31 |
| 14 |
|
Bayern München II | 28 | 8 | 7 | 13 | 24:37 | -13 | 31 |
| 15 |
|
Jahn Regensburg | 28 | 7 | 9 | 12 | 35:39 | -4 | 30 |
| 16 |
|
Eintracht Trier | 28 | 8 | 6 | 14 | 34:50 | -16 | 30 |
| 17 |
|
SC Pfullendorf | 28 | 7 | 8 | 13 | 22:32 | -10 | 29 |
| 18 |
|
1. FC Eschborn | 28 | 1 | 7 | 20 | 12:60 | -48 | 10 |
