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| 25.11.2020 | 15:30 | Fortuna Düsseldorf II | - | Bor. Mönchengladbach II | 2:1 (1:0) | |
| 17:30 | Borussia Dortmund II | - | SV Rödinghausen | 1:2 (0:1) | ||
| 18:00 | Fortuna Köln | - | Preußen Münster | 2:0 (1:0) | ||
| 18:00 | Sportfreunde Lotte | - | Alemannia Aachen | 1:0 (1:0) | ||
| 18:00 | SV Lippstadt 08 | - | Rot-Weiß Oberhausen | 1:1 (0:0) | ||
| 19:30 | Bonner SC | - | SV 19 Straelen | 0:1 (0:1) | ||
| 19:30 | FC Wegberg-Beeck | - | 1. FC Köln II | 0:4 (0:2) | ||
| 19:30 | Rot Weiss Ahlen | - | FC Schalke 04 II | 1:1 (0:0) | ||
| 19:30 | Rot-Weiss Essen | - | Wuppertaler SV | 6:1 (2:1) | ||
| 19:30 | SC Wiedenbrück | - | VfB Homberg | 0:0 (0:0) |
| » Tabelle | Heim | Auswärts | Hinrunde | Rückrunde | 1. Halbzeit | 2. Halbzeit |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Rot-Weiss Essen | 16 | 12 | 4 | 0 | 37:8 | 29 | 40 |
| 2 |
|
Borussia Dortmund II | 16 | 11 | 4 | 1 | 42:14 | 28 | 37 |
| 3 |
|
Fortuna Düsseldorf II | 16 | 9 | 5 | 2 | 33:12 | 21 | 32 |
| 4 |
|
Preußen Münster | 16 | 10 | 2 | 4 | 26:14 | 12 | 32 |
| 5 |
|
Fortuna Köln | 16 | 8 | 5 | 3 | 34:20 | 14 | 29 |
| 6 |
|
1. FC Köln II | 16 | 7 | 6 | 3 | 24:15 | 9 | 27 |
| 7 |
|
Bor. Mönchengladbach II | 16 | 7 | 3 | 6 | 27:22 | 5 | 24 |
| 8 |
|
SV Rödinghausen | 16 | 6 | 5 | 5 | 19:16 | 3 | 23 |
| 9 |
|
Alemannia Aachen | 17 | 6 | 5 | 6 | 13:13 | 0 | 23 |
| 10 |
|
SV 19 Straelen | 17 | 6 | 5 | 6 | 20:25 | -5 | 23 |
| 11 |
|
FC Schalke 04 II | 16 | 5 | 7 | 4 | 18:17 | 1 | 22 |
| 12 |
|
SC Wiedenbrück | 16 | 4 | 8 | 4 | 27:27 | 0 | 20 |
| 13 |
|
Wuppertaler SV | 17 | 5 | 3 | 9 | 18:30 | -12 | 18 |
| 14 |
|
Rot-Weiß Oberhausen | 16 | 3 | 8 | 5 | 22:26 | -4 | 17 |
| 15 |
|
FC Wegberg-Beeck | 16 | 4 | 5 | 7 | 18:25 | -7 | 17 |
| 16 |
|
SV Bergisch Gladbach 09 | 16 | 4 | 5 | 7 | 16:24 | -8 | 17 |
| 17 |
|
VfB Homberg | 17 | 4 | 2 | 11 | 14:32 | -18 | 14 |
| 18 |
|
Sportfreunde Lotte | 16 | 3 | 4 | 9 | 17:35 | -18 | 13 |
| 19 |
|
SV Lippstadt 08 | 16 | 1 | 9 | 6 | 13:26 | -13 | 12 |
| 20 |
|
Bonner SC | 16 | 3 | 2 | 11 | 13:31 | -18 | 11 |
| 21 |
|
Rot Weiss Ahlen | 16 | 1 | 5 | 10 | 16:35 | -19 | 8 |
| Aufstieg | |
| Abstieg |
