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| H | Team Aargau | - | BSC Young Boys | 1:2 (0:2) | ||
| R | BSC Young Boys | - | Team Aargau | 2:1 (2:0) | ||
| H: 28.05.2022 13:30 | R: 04.06.2022 13:30 | Sieger: BSC Young Boys | ||||
| H | FCO St. Gallen/Wil | - | Servette FC | 3:0 (2:0) | ||
| R | Servette FC | - | FCO St. Gallen/Wil | 1:0 (0:0) | ||
| H: 28.05.2022 14:00 | R: 04.06.2022 14:00 | Sieger: FCO St. Gallen/Wil | ||||
| H | Team FC Luzern/SC Kriens | - | FC Basel | 1:6 (1:3) | ||
| R | FC Basel | - | Team FC Luzern/SC Kriens | 2:3 (1:2) | ||
| H: 28.05.2022 14:00 | R: 04.06.2022 14:00 | Sieger: FC Basel | ||||
| H | Grasshopper Club Zürich | - | FC Zürich | 0:4 (0:2) | ||
| R | FC Zürich | - | Grasshopper Club Zürich | 1:4 (1:1) | ||
| H: 29.05.2022 14:00 | R: 04.06.2022 19:00 | Sieger: FC Zürich | ||||
