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| 01.05.2021 | 17:00 | FK Senica | - | FC Nitra | 1:0 (0:0) | |
| 17:00 | MFK Zemplín Michalovce | - | MFK Ružomberok | 2:1 (1:1) | ||
| 17:00 | ŠKF Sereď | - | FK Pohronie | 0:1 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
MFK Ružomberok | 29 | 9 | 8 | 12 | 38:42 | -4 | 35 |
| 2 |
|
ŠKF Sereď | 29 | 9 | 7 | 13 | 30:45 | -15 | 34 |
| 3 |
|
FK Pohronie | 29 | 7 | 12 | 10 | 37:38 | -1 | 33 |
| 4 |
|
FK Senica | 29 | 8 | 7 | 14 | 29:46 | -17 | 31 |
| 5 |
|
MFK Zemplín Michalovce | 29 | 7 | 9 | 13 | 28:51 | -23 | 30 |
| 6 |
|
FC Nitra | 29 | 7 | 6 | 16 | 26:48 | -22 | 27 |
| Relegation | |
| Abstieg |
