 |
 |
|
|
| 10.09.2021 | 17:00 | Zlaté Moravce | - | MFK Ružomberok | 2:2 (0:1) | |
| 11.09.2021 | 18:00 | MŠK Žilina | - | AS Trenčín | 1:3 (1:2) | |
| 18:00 | MFK Zemplín Michalovce | - | Spartak Trnava | 1:2 (0:1) | ||
| 18:00 | FK Senica | - | FK Pohronie | 1:0 (0:0) | ||
| 18:00 | ŠKF Sereď | - | Tatran Liptovský Mikuláš | 2:0 (2:0) | ||
| 12.09.2021 | 17:00 | FC DAC 1904 | - | Slovan Bratislava | 1:1 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Slovan Bratislava | 7 | 5 | 1 | 1 | 15:5 | 10 | 16 |
| 2 |
|
Spartak Trnava | 7 | 4 | 2 | 1 | 12:4 | 8 | 14 |
| 3 |
|
MŠK Žilina | 7 | 4 | 1 | 2 | 13:7 | 6 | 13 |
| 4 |
|
AS Trenčín | 7 | 3 | 3 | 1 | 11:6 | 5 | 12 |
| 5 |
|
FK Senica | 7 | 3 | 3 | 1 | 7:7 | 0 | 12 |
| 6 |
|
MFK Ružomberok | 7 | 2 | 5 | 0 | 7:5 | 2 | 11 |
| 7 |
|
FC DAC 1904 | 7 | 2 | 3 | 2 | 10:9 | 1 | 9 |
| 8 |
|
ŠKF Sereď | 7 | 2 | 2 | 3 | 6:8 | -2 | 8 |
| 9 |
|
MFK Zemplín Michalovce | 7 | 2 | 1 | 4 | 9:11 | -2 | 7 |
| 10 |
|
Zlaté Moravce | 7 | 1 | 2 | 4 | 5:14 | -9 | 5 |
| 11 |
|
FK Pohronie | 7 | 1 | 1 | 5 | 4:11 | -7 | 4 |
| 12 |
|
Tatran Liptovský Mikuláš | 7 | 1 | 0 | 6 | 6:18 | -12 | 3 |
| Playoffs | |
| Relegation |
