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| 09.04.2021 | 15:00 | Eskişehirspor | - | Giresunspor | 0:5 (0:3) | |
| 15:00 | Keçiörengücü | - | Altınordu FK | 5:3 (2:0) | ||
| 18:00 | İstanbulspor AŞ | - | Tuzlaspor | 2:1 (0:1) | ||
| 10.04.2021 | 12:30 | Altay Izmir | - | Boluspor | 0:1 (0:1) | |
| 12:30 | Bandırmaspor | - | Menemen Belediyespor | 2:2 (1:0) | ||
| 15:00 | Samsunspor | - | Balıkesirspor | 1:0 (0:0) | ||
| 18:00 | Akhisar Belediyespor | - | Adana Demirspor | 2:3 (1:2) | ||
| 11.04.2021 | 15:00 | Ümraniyespor | - | Bursaspor | 2:1 (1:1) | |
| 18:00 | Adanaspor | - | Ankaraspor | 1:2 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Giresunspor | 29 | 18 | 6 | 5 | 47:20 | 27 | 60 |
| 2 |
|
Samsunspor | 29 | 16 | 9 | 4 | 45:26 | 19 | 57 |
| 3 |
|
Adana Demirspor | 29 | 16 | 7 | 6 | 50:26 | 24 | 55 |
| 4 |
|
Altay Izmir | 29 | 17 | 2 | 10 | 55:31 | 24 | 53 |
| 5 |
|
Altınordu FK | 29 | 15 | 7 | 7 | 49:41 | 8 | 52 |
| 6 |
|
İstanbulspor AŞ | 29 | 15 | 6 | 8 | 51:31 | 20 | 51 |
| 7 |
|
Keçiörengücü | 29 | 14 | 7 | 8 | 39:23 | 16 | 49 |
| 8 |
|
Ümraniyespor | 29 | 11 | 8 | 10 | 35:37 | -2 | 41 |
| 9 |
|
Tuzlaspor | 29 | 12 | 5 | 12 | 37:43 | -6 | 41 |
| 10 |
|
Bursaspor | 29 | 12 | 4 | 13 | 47:46 | 1 | 40 |
| 11 |
|
Bandırmaspor | 29 | 11 | 6 | 12 | 37:37 | 0 | 39 |
| 12 |
|
Boluspor | 29 | 10 | 5 | 14 | 30:32 | -2 | 35 |
| 13 |
|
Balıkesirspor | 29 | 8 | 8 | 13 | 30:41 | -11 | 32 |
| 14 |
|
Adanaspor | 29 | 8 | 7 | 14 | 38:43 | -5 | 31 |
| 15 |
|
Menemen Belediyespor | 29 | 6 | 12 | 11 | 32:47 | -15 | 30 |
| 16 |
|
Akhisar Belediyespor | 29 | 7 | 4 | 18 | 31:51 | -20 | 25 |
| 17 |
|
Ankaraspor | 29 | 5 | 7 | 17 | 24:48 | -24 | 22 |
| 18 |
|
Eskişehirspor | 29 | 1 | 8 | 20 | 19:73 | -54 | 8 |
| Aufstieg | |
| Playoffs | |
| Abstieg |
