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| 26.11.2021 | 12:00 | Diyarbekirspor | - | Serik Belediyespor | 3:0 (2:0) | |
| 27.11.2021 | 11:00 | Adıyamanspor | - | Sivas Belediyespor | 3:1 (0:0) | |
| 11:00 | Afjet Afyonspor | - | Kahramanmaraşspor | 7:0 (3:0) | ||
| 11:00 | Ankaraspor | - | Bodrumspor | 1:0 (1:0) | ||
| 11:00 | Ergene Velimeşe | - | Turgutluspor | 1:2 (1:0) | ||
| 11:00 | Hekimoğlu Trabzon | - | Çorum FK | 1:1 (0:0) | ||
| 11:00 | Niğde Anadolu FK | - | Bayburt İl Özel İdare | 1:2 (0:1) | ||
| 11:00 | Somaspor | - | Vanspor FK | 2:0 (1:0) | ||
| 11:30 | Inegölspor | - | Sarıyer SK | 1:0 (0:0) | ||
| 13:00 | Sakaryaspor | - | Etimesgut Belediyespor | 3:0 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Sakaryaspor | 15 | 10 | 5 | 0 | 30:5 | 25 | 35 |
| 2 |
|
Hekimoğlu Trabzon | 15 | 9 | 6 | 0 | 28:9 | 19 | 33 |
| 3 |
|
Sivas Belediyespor | 15 | 9 | 3 | 3 | 29:9 | 20 | 30 |
| 4 |
|
Çorum FK | 15 | 7 | 7 | 1 | 22:8 | 14 | 28 |
| 5 |
|
Bayburt İl Özel İdare | 15 | 8 | 3 | 4 | 21:14 | 7 | 27 |
| 6 |
|
Bodrumspor | 15 | 8 | 2 | 5 | 25:12 | 13 | 26 |
| 7 |
|
Afjet Afyonspor | 15 | 6 | 7 | 2 | 29:15 | 14 | 25 |
| 8 |
|
Ankaraspor | 15 | 7 | 4 | 4 | 26:16 | 10 | 25 |
| 9 |
|
Somaspor | 15 | 7 | 4 | 4 | 24:19 | 5 | 25 |
| 10 |
|
Vanspor FK | 15 | 7 | 4 | 4 | 21:21 | 0 | 25 |
| 11 |
|
Inegölspor | 15 | 6 | 3 | 6 | 18:21 | -3 | 21 |
| 12 |
|
Serik Belediyespor | 15 | 6 | 2 | 7 | 19:23 | -4 | 20 |
| 13 |
|
Etimesgut Belediyespor | 15 | 5 | 4 | 6 | 16:21 | -5 | 19 |
| 14 |
|
Diyarbekirspor | 15 | 5 | 3 | 7 | 18:17 | 1 | 18 |
| 15 |
|
Turgutluspor | 15 | 4 | 5 | 6 | 19:27 | -8 | 17 |
| 16 |
|
Sarıyer SK | 15 | 3 | 3 | 9 | 14:24 | -10 | 12 |
| 17 |
|
Ergene Velimeşe | 15 | 3 | 2 | 10 | 13:31 | -18 | 11 |
| 18 |
|
Adıyamanspor | 15 | 3 | 1 | 11 | 18:30 | -12 | 10 |
| 19 |
|
Niğde Anadolu FK | 15 | 1 | 2 | 12 | 10:40 | -30 | 5 |
| 20 |
|
Kahramanmaraşspor | 15 | 1 | 0 | 14 | 6:44 | -38 | 3 |
| Aufstieg | |
| Playoffs | |
| Abstieg |
