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| 06.03.2021 | 14:00 | Denizlispor | - | Yeni Malatyaspor | 3:2 (2:1) | |
| 17:00 | Beşiktaş | - | Gaziantep FK | 2:1 (1:0) | ||
| 07.03.2021 | 11:30 | Fatih Karagümrük SK | - | MKE Ankaragücü | 0:1 (0:0) | |
| 14:00 | Gençlerbirliği | - | İstanbul Başakşehir | 0:1 (0:0) | ||
| 14:00 | Hatayspor | - | Kayserispor | 1:3 (0:2) | ||
| 17:00 | Galatasaray | - | Sivasspor | 2:2 (1:2) | ||
| 08.03.2021 | 14:00 | Antalyaspor | - | Kasımpaşa SK | 1:1 (1:0) | |
| 14:00 | Trabzonspor | - | Alanyaspor | 1:3 (0:0) | ||
| 17:00 | Göztepe | - | BB Erzurumspor | 3:1 (1:0) | ||
| 17:00 | Konyaspor | - | Fenerbahçe | 0:3 (0:2) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Beşiktaş | 27 | 19 | 3 | 5 | 59:27 | 32 | 60 |
| 2 |
|
Galatasaray | 28 | 18 | 4 | 6 | 55:23 | 32 | 58 |
| 3 |
|
Fenerbahçe | 28 | 18 | 4 | 6 | 52:28 | 24 | 58 |
| 4 |
|
Trabzonspor | 28 | 15 | 6 | 7 | 35:29 | 6 | 51 |
| 5 |
|
Alanyaspor | 28 | 13 | 7 | 8 | 44:28 | 16 | 46 |
| 6 |
|
Hatayspor | 28 | 13 | 7 | 8 | 48:35 | 13 | 46 |
| 7 |
|
Gaziantep FK | 28 | 11 | 10 | 7 | 40:32 | 8 | 43 |
| 8 |
|
Fatih Karagümrük SK | 28 | 11 | 8 | 9 | 43:37 | 6 | 41 |
| 9 |
|
Göztepe | 28 | 10 | 9 | 9 | 40:33 | 7 | 39 |
| 10 |
|
Antalyaspor | 28 | 7 | 15 | 6 | 26:31 | -5 | 36 |
| 11 |
|
Sivasspor | 27 | 7 | 13 | 7 | 31:32 | -1 | 34 |
| 12 |
|
Konyaspor | 27 | 8 | 8 | 11 | 33:34 | -1 | 32 |
| 13 |
|
Yeni Malatyaspor | 28 | 7 | 10 | 11 | 35:39 | -4 | 31 |
| 14 |
|
Kayserispor | 27 | 8 | 7 | 12 | 22:32 | -10 | 31 |
| 15 |
|
Kasımpaşa SK | 28 | 8 | 6 | 14 | 31:44 | -13 | 30 |
| 16 |
|
İstanbul Başakşehir | 28 | 7 | 8 | 13 | 30:45 | -15 | 29 |
| 17 |
|
Çaykur Rizespor | 27 | 6 | 10 | 11 | 31:44 | -13 | 28 |
| 18 |
|
MKE Ankaragücü | 27 | 7 | 5 | 15 | 31:45 | -14 | 26 |
| 19 |
|
BB Erzurumspor | 28 | 6 | 8 | 14 | 27:46 | -19 | 26 |
| 20 |
|
Denizlispor | 27 | 6 | 6 | 15 | 26:48 | -22 | 24 |
| 21 |
|
Gençlerbirliği | 27 | 5 | 6 | 16 | 22:49 | -27 | 21 |
| Champions League Quali. | |
| Europa Conference League Quali. | |
| Abstieg |
