| Vorrunde | 28.07.2022 | Deportivo Malacateco | - | Sporting San Miguelito | 1:1 | ||||
| Vorrunde | 04.08.2022 | Sporting San Miguelito | - | Deportivo Malacateco | 3:0 | ||||
| Achtelfinale | 17.08.2022 | Sporting San Miguelito | - | Tauro FC | 0:1 | ||||
| Achtelfinale | 24.08.2022 | Tauro FC | - | Sporting San Miguelito | 1:1 |
Panama