| 1. Spieltag | 16.07.2022 | Tacuary | - | Guaireña FC | 0:0 | ||||
| 2. Spieltag | 21.07.2022 | Tacuary | - | Cerro Porteño | 0:1 | ||||
| 4. Spieltag | 31.07.2022 | Tacuary | - | Club Olimpia | 2:1 | ||||
| 5. Spieltag | 06.08.2022 | General Caballero DJLM | - | Tacuary | 0:4 | ||||
| 6. Spieltag | 16.08.2022 | Tacuary | - | Resistencia SC | 1:1 | ||||
| 7. Spieltag | 21.08.2022 | 12 de Octubre de Itauguá | - | Tacuary | 0:2 | ||||
| 8. Spieltag | 29.08.2022 | Tacuary | - | Sol de América | 1:0 | ||||
| 9. Spieltag | 04.09.2022 | Club Nacional | - | Tacuary | 1:0 | ||||
| 10. Spieltag | 11.09.2022 | Tacuary | - | Guaraní | 2:0 | ||||
| 11. Spieltag | 14.09.2022 | Libertad | - | Tacuary | 2:0 | ||||
| 12. Spieltag | 19.09.2022 | Guaireña FC | - | Tacuary | 1:0 |  |
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| 13. Spieltag | 26.09.2022 | Cerro Porteño | - | Tacuary | 5:0 | ||||
| 14. Spieltag | 02.10.2022 | Tacuary | - | Sportivo Ameliano | 1:1 | ||||
| 15. Spieltag | 06.10.2022 | Club Olimpia | - | Tacuary | 1:0 |
Paraguay