| ANAPROF | 22.08.21 | Veraguas Club Deportivo | - | Herrera FC | 1:1 | ||||
| ANAPROF | 03.10.21 | Sporting San Miguelito | - | Herrera FC | 1:1 |  |
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| ANAPROF | 13.11.21 | Herrera FC | - | San Francisco FC | 2:1 | ||||
| ANAPROF | 12.12.21 | Tauro FC | - | Herrera FC | 3:0 | ||||
| ANAPROF | 26.03.22 | San Francisco FC | - | Sporting San Miguelito | 0:1 | ||||
| ANAPROF | 27.04.22 | San Francisco FC | - | Atlético Chiriquí | 2:2 |
Panama