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| 24.08.2010 | 14:30 | FK Imereti Khoni | - | Baia Zugdidi | 0:1 | |
| 14:30 | FC Khobi | - | Dinamo Batumi | 1:2 | ||
| 14:30 | FC Norchi Dinamoeli | - | FC Gagra | 1:3 | ||
| 14:30 | Mertskhali Ozurgeti | - | Torpedo Kutaisi | 0:4 | ||
| 14:30 | FC Chiatura | - | FC Samtredia | 1:6 | ||
| 14:30 | FK Adeli Batumi | - | Kolkheti Poti | 0:2 | ||
| 14:30 | FC Meshakhte Tkibuli | - | Chikhura Sachkhere | 1:3 | ||
| 14:30 | Iveria Khashuri | - | Spartak Tskhinvali | 0:2 | ||
| 14:30 | Samgurali Tskhaltubo | - | FC Merani Martvili | 0:2 | ||
| 14:30 | Dila Gori | - | Lokomotiv Tbilisi | 3:4 i.E. | ||
| 14:30 | Squri Tsalenjikha | - | Guria Lanchkhuti | 2:0 | ||
| 14:30 | Zooveti Tbilisi | - | Sioni Bolnisi | 0:2 |
