| 1. Spieltag | 06.09.2022 | Go Ahead Eagles [U21] | - | Roda JC Kerkrade [U21] | 1:4 | ||||
| 2. Spieltag | 10.09.2022 | NAC Breda [U21] | - | Go Ahead Eagles [U21] | 4:2 | ||||
| 3. Spieltag | 17.09.2022 | NEC Nijmegen [U21] | - | Go Ahead Eagles [U21] | 2:1 | ||||
| 4. Spieltag | 01.10.2022 | Go Ahead Eagles [U21] | - | VVV-Venlo [U21] | 1:4 | ||||
| 5. Spieltag | 08.10.2022 | Twente/Heracles [U21] | - | Go Ahead Eagles [U21] | 2:0 | ||||
| 6. Spieltag | 15.10.2022 | Go Ahead Eagles [U21] | - | FC Den Bosch [U21] | 2:2 | ||||
| 7. Spieltag | 22.10.2022 | Vitesse [U21] | - | Go Ahead Eagles [U21] | 2:2 | ||||
| 8. Spieltag | 29.10.2022 | Roda JC Kerkrade [U21] | - | Go Ahead Eagles [U21] | 1:2 | ||||
| 9. Spieltag | 05.11.2022 | Go Ahead Eagles [U21] | - | NAC Breda [U21] | 0:0 | ||||
| 10. Spieltag | 12.11.2022 | Go Ahead Eagles [U21] | - | NEC Nijmegen [U21] | 3:1 | ||||
| 11. Spieltag | 19.11.2022 | VVV-Venlo [U21] | - | Go Ahead Eagles [U21] | 1:2 | ||||
| 12. Spieltag | 25.11.2022 | Go Ahead Eagles [U21] | - | Twente/Heracles [U21] | 0:3 | ||||
| 13. Spieltag | 03.12.2022 | FC Den Bosch [U21] | - | Go Ahead Eagles [U21] | 1:1 | ||||
| 14. Spieltag | 17.12.2022 | Go Ahead Eagles [U21] | - | Vitesse [U21] | 2:0 |
Niederlande