| Vorrunde | 09.03.2022 | Liverpool | - | River Plate | 0:1 | ||||
| Vorrunde | 16.03.2022 | River Plate | - | Liverpool | 2:0 |  |
 |
||
| Gruppe B | 08.04.2022 | River Plate | - | Racing Club | 0:1 | ||||
| Gruppe B | 14.04.2022 | FBC Melgar | - | River Plate | 2:0 | ||||
| Gruppe B | 28.04.2022 | Cuiabá - MT | - | River Plate | 1:2 | ||||
| Gruppe B | 04.05.2022 | River Plate | - | FBC Melgar | 1:2 | ||||
| Gruppe B | 19.05.2022 | River Plate | - | Cuiabá - MT | 1:2 | |
Uruguay