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| 24.05.2022 | 19:00 | Höttur/Huginn | - | Ægir | 1:3 | |
| 20:00 | Sindri Höfn | - | ÍA Akranes | 3:5 | ||
| 20:00 | UMF Selfoss | - | ÍF Magni | 5:3 i.E. | ||
| 20:00 | IF Vestri | - | UMF Afturelding | 2:3 n.V. | ||
| 21:15 | Hvíti riddarinn | - | Kórdrengir | 0:2 | ||
| 21:15 | UMF Grindavík | - | ÍR Reykjavík | 1:2 | ||
| 21:15 | HK Kópavogur | - | Grótta | 3:1 | ||
| 21:45 | Dalvík/Reynir | - | Þór Akureyri | 2:0 | ||
| 25.05.2022 | 20:00 | Fylkir Reykjavík | - | ÍBV Vestmannaeyjar | 2:1 | |
| 21:15 | FH Hafnarfjörður | - | Kári | 3:0 | ||
| 21:15 | Keflavík ÍF | - | UMF Njarðvík | 1:4 | ||
| 21:45 | UMF Stjarnan | - | KR Reykjavík | 0:3 | ||
| 26.05.2022 | 16:00 | Fram Reykjavík | - | Leiknir Reykjavík | 3:2 n.V. | |
| 18:00 | KA Akureyri | - | Reynir Sandgerði | 4:1 | ||
| 21:15 | Haukar Hafnarfjörður | - | Víkingur Reykjavík | 0:7 | ||
| 21:45 | Breiðablik | - | Valur Reykjavík | 6:2 (2:2) |
