| 2. Runde | 22.07.2021 | Viktoria Plzeň | - | Dinamo Brest | 2:1 | ||||
| 2. Runde | 29.07.2021 | Dinamo Brest | - | Viktoria Plzeň | 1:2 |  |
|||
| 3. Runde | 05.08.2021 | The New Saints | - | Viktoria Plzeň | 4:2 | ||||
| 3. Runde | 12.08.2021 | Viktoria Plzeň | - | The New Saints | 4:1 i.E. | ||||
| Playoffs | 19.08.2021 | Viktoria Plzeň | - | CSKA Sofia | 2:0 | ||||
| Playoffs | 26.08.2021 | CSKA Sofia | - | Viktoria Plzeň | 3:0 n.V. |
DR Kongo