| 2. Runde | 09.03.2021 | Santos FC | - | Deportivo Lara | 2:1 | ||||
| 2. Runde | 16.03.2021 | Deportivo Lara | - | Santos FC | 1:1 | ||||
| 3. Runde | 07.04.2021 | San Lorenzo | - | Santos FC | 1:3 | ||||
| 3. Runde | 14.04.2021 | Santos FC | - | San Lorenzo | 2:2 |  |
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| Gruppe 3 | 21.04.2021 | Santos FC | - | Barcelona | 0:2 | ||||
| Gruppe 3 | 28.04.2021 | Boca Juniors | - | Santos FC | 2:0 | |
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| Gruppe 3 | 05.05.2021 | Santos FC | - | The Strongest | 5:0 | ||||
| Gruppe 3 | 19.05.2021 | The Strongest | - | Santos FC | 2:1 | ||||
| Gruppe 3 | 27.05.2021 | Barcelona | - | Santos FC | 3:1 |
Brasilien